Histone Deacetylase 3 antibody
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WB P IF IP ResetRabbit anti Histone Deacetylase 3
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- Histone Deacetylase 3
Antibody Quality and Performance Guarantee
| Rabbit anti histone deacetylase 3 antibody recognizes histone deacetylase 3 also known as HDAC3. Histone deacetylases are chromatin-modifying enzymes that are involved in regulation of many aspects of cell biology including tissue differentiation, autophagy, apoptosis, migration, mitosis and angiogenesis. Class I HDACs, which include HDAC1, 2, 3 and 8 are ubiquitously expressed in all tissues and have predominantly nuclear localization. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to histone deacetylase 3 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
50% Glycerol - Immunogen
- Recombinant human histone deacetylase 3
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Chromatin Immunoprecipitation |  |
1/20 | 1/100 |
| Immunofluorescence | |
1/50 | 1/200 |
| Immunohistology - Paraffin | |
1/50 | 1/100 |
| Immunoprecipitation | |
1/50 | 1/200 |
| Western Blotting | |
1/500 | 1/2000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti histone deacetylase 3 antibody detects a band of approximately 49 kDa in cell lysates under reducing conditions
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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| List Price | Your Price | ||||||
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| Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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| List Price | Your Price | ||||||
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| Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
| Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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| Description | Sheep anti Rabbit IgG:FITC | ||||||
| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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| Description | Sheep anti Rabbit IgG:RPE | ||||||
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml | Log in | |||
| List Price | Your Price | ||||||
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| Description | TidyBlot Western Blot Detection Reagent:HRP | ||||||
- Synonyms
- HDAC3
- UniProt
- O15379
- Entrez Gene
- HDAC3
- GO Terms
- GO:0000118 histone deacetylase complex
- GO:0003714 transcription corepressor activity
- GO:0004407 histone deacetylase activity
- GO:0005737 cytoplasm
- GO:0005876 spindle microtubule
- GO:0006916 anti-apoptosis
- GO:0008134 transcription factor binding
- GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
- GO:0016564 transcription repressor activity
- View More GO Terms
- GO:0017053 transcriptional repressor complex
- GO:0042826 histone deacetylase binding
- GO:0044255 cellular lipid metabolic process
- GO:0045786 negative regulation of cell cycle
- GO:0046329 negative regulation of JNK cascade
- GO:0048011 nerve growth factor receptor signaling pathway
- GO:0051225 spindle assembly
AHP2476
141435
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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