Histone Deacetylase 2 antibody

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Rabbit anti Histone Deacetylase 2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
AHP2309 IC WB 50 µg
Rabbit anti Histone deacetylase 2 antibody recognizes histone deacetylase 2 (HDAC2). Histone acetylation and deacetylation play important roles in modifying chromatin structure and regulating eukaryotic gene expression. HDAC2 has been characterized as a class I HDAC enzyme, which is related to the yeast transcriptional regulator Rpd3p.

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
Chicken Expected from Sequence
Hamster Expected from Sequence
Dog Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
30% Glycerol
0.5% Bovine Serum Albumin
0.01% Thiomersal
Immunogen
Synthetic peptide surrounding amino acid 479 of human HDAC2
Approx. Protein Concentrations
IgG concentration 0.2 mg/ml

Storage Information

Storage
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
12 months from date of despatch

More Information

UniProt
Q92769 Related reagents
Entrez Gene
HDAC2 Related reagents
GO Terms
GO:0003682 chromatin binding
GO:0007596 blood coagulation
GO:0004407 histone deacetylase activity
GO:0005737 cytoplasm
GO:0006338 chromatin remodeling
GO:0006344 maintenance of chromatin silencing
GO:0008134 transcription factor binding
GO:0008284 positive regulation of cell proliferation
GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
GO:0010870 positive regulation of receptor biosynthetic process
GO:0016358 dendrite development
GO:0016563 transcription activator activity
GO:0016566 specific transcriptional repressor activity
GO:0016575 histone deacetylation
GO:0016580 Sin3 complex
GO:0016581 NuRD complex
GO:0019899 enzyme binding
GO:0032967 positive regulation of collagen biosynthetic process
GO:0035098 ESC/E(Z) complex
GO:0043433 negative regulation of transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0045347 negative regulation of MHC class II biosynthetic process
GO:0045786 negative regulation of cell cycle
GO:0045862 positive regulation of proteolysis
GO:0048011 nerve growth factor receptor signaling pathway
Regulatory
For research purposes only

Applications of Histone Deacetylase 2 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunocytochemistry 10 20 ug/ml
Western Blotting 0.5 4.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti Histone deacetylase 2 recognizes a band of approximately 55 kDa in Jurkat cell lysate, mouse small intestine tissue lysate and rat kidney tissue lysate

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Sheep anti Rabbit IgG:Biotin 2AB02B 1 ml C E P WB
Goat anti Rabbit IgG (Fc):Biotin STAR121B 1 mg E WB
Goat anti Rabbit IgG (Fc):FITC STAR121F 1 mg F
Goat anti Rabbit IgG (Fc):HRP STAR121P 1 mg E WB
Goat anti Rabbit IgG (H/L):HRP STAR124P 1 mg C E WB
Sheep anti Rabbit IgG:FITC STAR34B 1 mg C F
Sheep anti Rabbit IgG:RPE STAR35A 1 ml F
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:DyLight®549 STAR36D549GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®649 STAR36D649GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA 0.1 mg F IF WB