Histone Deacetylase 2 antibody
Rabbit anti Histone deacetylase 2 antibody recognizes histone deacetylase 2 (HDAC2). Histone acetylation and deacetylation play important roles in modifying chromatin structure and regulating eukaryotic gene expression. HDAC2 has been characterized as a class I HDAC enzyme, which is related to the yeast transcriptional regulator Rpd3p.
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat Chicken Expected from Sequence Hamster Expected from Sequence Dog Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 30% Glycerol
0.5% Bovine Serum Albumin
0.01% Thiomersal - Immunogen
- Synthetic peptide surrounding amino acid 479 of human HDAC2
- Approx. Protein Concentrations
- IgG concentration 0.2 mg/ml
Storage Information
- Storage
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q92769
- Entrez Gene
- HDAC2
- GO Terms
- GO:0003682 chromatin binding
- GO:0007596 blood coagulation
- GO:0004407 histone deacetylase activity
- GO:0005737 cytoplasm
- GO:0006338 chromatin remodeling
- GO:0006344 maintenance of chromatin silencing
- GO:0008134 transcription factor binding
- GO:0008284 positive regulation of cell proliferation
- GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
- GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
- GO:0010870 positive regulation of receptor biosynthetic process
- GO:0016358 dendrite development
- GO:0016563 transcription activator activity
- GO:0016566 specific transcriptional repressor activity
- GO:0016575 histone deacetylation
- GO:0016580 Sin3 complex
- GO:0016581 NuRD complex
- GO:0019899 enzyme binding
- GO:0032967 positive regulation of collagen biosynthetic process
- GO:0035098 ESC/E(Z) complex
- GO:0043433 negative regulation of transcription factor activity
- GO:0043565 sequence-specific DNA binding
- GO:0045347 negative regulation of MHC class II biosynthetic process
- GO:0045786 negative regulation of cell cycle
- GO:0045862 positive regulation of proteolysis
- GO:0048011 nerve growth factor receptor signaling pathway
- Regulatory
- For research purposes only
Applications of Histone Deacetylase 2 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunocytochemistry | 10 | 20 ug/ml | |
| Western Blotting | 0.5 | 4.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti Histone deacetylase 2 recognizes a band of approximately 55 kDa in Jurkat cell lysate, mouse small intestine tissue lysate and rat kidney tissue lysate
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
|
|
| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
|
|
| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
|
|
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
|
|
| Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
|
|
| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
|
|
| Sheep anti Rabbit IgG:DyLight®488 | STAR36D488GA | F IF WB | 0.1 mg | ||
| Sheep anti Rabbit IgG:DyLight®680 | STAR36D680GA | F IF WB | 0.1 mg | ||
| Sheep anti Rabbit IgG:Dylight®800 | STAR36D800GA | F IF WB | 0.1 mg |
Fluorescent Spectraviewer
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