Histone Deacetylase 1 antibody

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Rabbit anti Histone Deacetylase 1

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified

Product Code	Applications	Pack Size	Your Price	List Price	Quantity
VPA00175 Datasheet	WB SDS	100 µl	Log in		Get Quote

Rabbit anti Human histone deacetylase 1 antibody recognizes histone deacetylase 1, also known as HDAC1.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.

Rabbit anti Human histone deacetylase 1 antibody detects a band of 62 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species

Human

Western Blotting

Anti histone deacetylase 1 detects a band of approximately 62 kDa in Jurkat cell lysates.

Species Cross-Reactivity

Target Species	Cross Reactivity
Mouse
Rat

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid

Preparation

Rabbit polyclonal antibody purified by affinity chromatography

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

0.09% Sodium Azide (NaN₃)
1% Bovine Serum Albumin
<50% Glycerol

Immunogen

Synthetic peptide corresponding to an internal region of human histone deacetylase 1

Storage Information

Storage: Store undiluted at -20^oC, avoiding repeated freeze thaw cycles.
Guarantee: 12 months from date of despatch

More Information

UniProt: Q13547
Entrez Gene: HDAC1
GO Terms: GO:0003700 sequence-specific DNA binding transcription factor activity; GO:0007596 blood coagulation; GO:0004407 histone deacetylase activity; GO:0005829 cytosol; GO:0006338 chromatin remodeling; GO:0006916 anti-apoptosis; GO:0008134 transcription factor binding; GO:0008284 positive regulation of cell proliferation; GO:0042802 identical protein binding; GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter; GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter; GO:0010870 positive regulation of receptor biosynthetic process; GO:0016563 transcription activator activity; GO:0016566 specific transcriptional repressor activity; GO:0016580 Sin3 complex; GO:0016581 NuRD complex; GO:0042826 histone deacetylase binding; GO:0043922 negative regulation by host of viral transcription; GO:0045786 negative regulation of cell cycle; GO:0048011 nerve growth factor receptor signaling pathway; GO:0070932 histone H3 deacetylation; GO:0070933 histone H4 deacetylation
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory: For research purposes only

Applications of Histone Deacetylase 1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description	Product Code	Applications	Pack Size	Your Price	List Price	Quantity
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in		Get Quote

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