HEREMANS-SCHMID Glycoprotein antibody
Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure (provided by RefSeq, Jul 2008).
Goat anti Human Heremans-Schmid glycoprotein antibody detects a band of 58 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
- Target Species
- Western Blotting
- Anti Heremans-Schmid glycoprotein detects a band of approximately 58 kDa in C6 cell lysates.
- Species Cross-Reactivity
Target Species Cross Reactivity Rat
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Goat polyclonal antibody prepared by ion exchange chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Recombinant human Heremans-Schmid glycoprotein processed to remove a 40 amino acid residue bridging peptide resulting in the mature form of the protein
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
- GO:0005515 protein binding
- GO:0001501 skeletal system development
- GO:0006953 acute-phase response
- GO:0004869 cysteine-type endopeptidase inhibitor activity
- GO:0005615 extracellular space
- GO:0006907 pinocytosis
- GO:0019210 kinase inhibitor activity
- GO:0030502 negative regulation of bone mineralization
- GO:0046627 negative regulation of insulin receptor signaling pathway
- GO:0050727 regulation of inflammatory response
- GO:0050766 positive regulation of phagocytosis
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- For research purposes only
Applications of HEREMANS-SCHMID Glycoprotein antibody
|Application Name||Verified||Min Dilution||Max Dilution|
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Secondary Antibodies Available
|Description||Product Code||Applications||Pack Size||List Price||Quantity|
|Donkey anti Sheep/Goat IgG:HRP||STAR88P||C E P WB||1 ml|