HEREMANS-SCHMID Glycoprotein antibody

100% Secure


Goat anti HEREMANS-SCHMID Glycoprotein

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00153
Datasheet
WB
SDS
100 µl loader

Goat anti Human Heremans-Schmid glycoprotein antibody recognizes Heremans-Schmid glycoprotein also known as Alpha-2-HS-glycoprotein , Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A and it is cleaved into the following 2 chains: Alpha-2-HS-glycoprotein chain A and Alpha-2-HS-glycoprotein chain B.

Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure (provided by RefSeq, Jul 2008).

Goat anti Human Heremans-Schmid glycoprotein antibody detects a band of 58 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti Heremans-Schmid glycoprotein detects a band of approximately 58 kDa in C6 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Goat polyclonal antibody prepared by ion exchange chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% BSA
Immunogen
Recombinant human Heremans-Schmid glycoprotein processed to remove a 40 amino acid residue bridging peptide resulting in the mature form of the protein

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
12 months from date of despatch

More Information

UniProt
P02765
Entrez Gene
AHSG
GO Terms
GO:0005515 protein binding
GO:0001501 skeletal system development
GO:0006953 acute-phase response
GO:0004869 cysteine-type endopeptidase inhibitor activity
GO:0005615 extracellular space
GO:0006907 pinocytosis
GO:0019210 kinase inhibitor activity
GO:0030502 negative regulation of bone mineralization
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0050727 regulation of inflammatory response
GO:0050766 positive regulation of phagocytosis
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of HEREMANS-SCHMID Glycoprotein antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Donkey anti Sheep/Goat IgG:HRP STAR88P C E P WB 1 ml loader