Heme Oxygenase 1 antibody

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Rabbit anti Heme Oxygenase 1

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified

Product Code	Applications	Pack Size	Your Price	List Price	Quantity
VPA00553 Datasheet	WB SDS	100 µl	Log in		Get Quote

Rabbit anti Human heme oxygenase 1 antibody recognizes heme oxygenase 1, also known as heat shock protein, 32-kD or HO1.

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family (provided by RefSeq, Jul 2008).

Rabbit anti Human heme oxygenase 1 antibody detects a band of 28 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species

Human

Western Blotting

Anti heme oxygenase 1 detects a band of approximately 28 kDa in A549 cell lysates.

Species Cross-Reactivity

Target Species	Cross Reactivity
Mouse

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid.

Preparation

Rabbit polyclonal antibody purified by affinity chromatography.

Buffer Solution

Phosphate buffered saline.

Preservative Stabilisers

0.09% Sodium Azide (NaN₃)
25% Glycerol

Immunogen

Human heme oxygenase 1 synthetic multiple antigenic peptide

Storage Information

Storage: Store undiluted at -20^oC, avoiding repeated freeze thaw cycles.
Guarantee: 12 months from date of despatch

More Information

UniProt: P09601
Entrez Gene: HMOX1
GO Terms: GO:0001525 angiogenesis; GO:0001935 endothelial cell proliferation; GO:0002246 wound healing involved in inflammatory response; GO:0002686 negative regulation of leukocyte migration; GO:0004392 heme oxygenase (decyclizing) activity; GO:0004871 signal transducer activity; GO:0005615 extracellular space; GO:0005789 endoplasmic reticulum membrane; GO:0005792 microsome; GO:0006788 heme oxidation; GO:0006879 cellular iron ion homeostasis; GO:0006916 anti-apoptosis; GO:0007243 intracellular protein kinase cascade; GO:0007588 excretion; GO:0008219 cell death; GO:0045909 positive regulation of vasodilation; GO:0014806 smooth muscle hyperplasia; GO:0019899 enzyme binding; GO:0020037 heme binding; GO:0034101 erythrocyte homeostasis; GO:0034383 low-density lipoprotein particle clearance; GO:0035094 response to nicotine; GO:0042167 heme catabolic process; GO:0042542 response to hydrogen peroxide; GO:0042803 protein homodimerization activity; GO:0051260 protein homooligomerization; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade; GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress; GO:0045080 positive regulation of chemokine biosynthetic process; GO:0045765 regulation of angiogenesis; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0048662 negative regulation of smooth muscle cell proliferation; GO:0055085 transmembrane transport
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory: For research purposes only.

Applications of Heme Oxygenase 1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description	Product Code	Applications	Pack Size	Your Price	List Price	Quantity
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in		Get Quote

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