Rabbit anti GOT1 antibody
recognizes glutamate oxaloacetate transaminase 1 (GOT1), also known as aspartate aminotransferase, cysteine aminotransferase cytoplasmic, cCAT and transaminase A. It coordinates the carbohydrate and amino acid metabolism (Zhou et al. 2018
). GOT1 supports long-term cell proliferation in KRAS mutated cancers (Son et al. 2013
- Target Species
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to GOT1 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
- Recombinant fusion protein containing a sequence corresponding to amino acids 244-413 of human GOT1
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
L-aspartate:2-oxoglutarate aminotransferase activity
aspartate catabolic process
pyridoxal phosphate binding
cellular response to insulin stimulus
response to glucocorticoid stimulus
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of GOT1 antibody
|Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti GOT1 antibody detects a band of approximately 42 kDa in various cell lysates under reducing conditions
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Secondary Antibodies Available
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