Glucose Transporter 1 antibody

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Rabbit anti Human Glut-1

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
OBT3133 IP WB 0.1 mg
Rabbit anti Human glucose transporter-1 antibody recognizes human Solute carrier family 2, facilitated glucose transporter member 1, also known as GLUT-1, glucose transporter type 1, erythrocyte/brain or HepG2 glucose transporter. GLUT-1 is a 492 amino acid ~50 kDa multi-pass transmembrane glycoprotein involved in cellular uptake of glucose.

Mutations in the GLUT1 gene can lead to a number of chronic conditions including GLUT1 deficiency syndrome 1 (GLUT1DS1), a neurologic disorder with wide phenotypic variability (Wang et al. 2005), GLUT1 deficiency syndrome 2 (GLUT1DS2), characterized by juvenile onset of excercise-induced dyskinesia (Weber et al. 2008), Epilepsy, idiopathic generalized 12 (EIG12) a condition presenting with repeated generalized seizures (Stranio et al. 2012) and Dystonia 9 (DYT9) a dominant inherited disorder presenting as a childhood onset of paroxysmal choreoathetosis and progressive spastic paraplegia (Weber et al. 2011).

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
Bovine Expected from Sequence
Cat Expected from Sequence
Dog Expected from Sequence
Horse Expected from Sequence
Pig Expected from Sequence
Rabbit Expected from Sequence
Rhesus Monkey Expected from Sequence
Sheep Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.1% Sodium Azide (NaN3)
Immunogen
12 amino acid peptide of the C-terminus of hGLUT-1 (LFHPLGADSQV) conjugated to KLH.
Approx. Protein Concentrations
IgG concentration 0.1mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P11166 Related reagents
Entrez Gene
SLC2A1 Related reagents
GO Terms
GO:0016021 integral to membrane
GO:0005624 membrane fraction
GO:0005975 carbohydrate metabolic process
GO:0006112 energy reserve metabolic process
GO:0006767 water-soluble vitamin metabolic process
GO:0050796 regulation of insulin secretion
GO:0030496 midbody
GO:0033300 dehydroascorbic acid transporter activity
GO:0042470 melanosome
GO:0055056 D-glucose transmembrane transporter activity
Regulatory
For research purposes only

Applications of Glucose Transporter 1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunoprecipitation 1 10ug/ml
Western Blotting 1 10ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Sheep anti Rabbit IgG:Biotin 2AB02B 1 ml C E P WB
Goat anti Rabbit IgG (Fc):Biotin STAR121B 1 mg E WB
Goat anti Rabbit IgG (Fc):FITC STAR121F 1 mg F
Goat anti Rabbit IgG (Fc):HRP STAR121P 1 mg E WB
Goat anti Rabbit IgG (H/L):HRP STAR124P 1 mg C E WB
Sheep anti Rabbit IgG:FITC STAR34B 1 mg C F
Sheep anti Rabbit IgG:RPE STAR35A 1 ml F
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:DyLight®549 STAR36D549GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®649 STAR36D649GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA 0.1 mg F IF WB

Useful Reagents Available

Description Product Code Pack Size Applications List Price Quantity
TidyBlot™ Western Blot Detection Reagent:HRP STAR209P 0.5 ml WB*