Glucose Transporter 1 antibody

Mutations in the GLUT1 gene can lead to a number of chronic conditions including GLUT1 deficiency syndrome 1 (GLUT1DS1), a neurologic disorder with wide phenotypic variability (Wang et al. 2005), GLUT1 deficiency syndrome 2 (GLUT1DS2), characterized by juvenile onset of excercise-induced dyskinesia (Weber et al. 2008), Epilepsy, idiopathic generalized 12 (EIG12) a condition presenting with repeated generalized seizures (Stranio et al. 2012) and Dystonia 9 (DYT9) a dominant inherited disorder presenting as a childhood onset of paroxysmal choreoathetosis and progressive spastic paraplegia (Weber et al. 2011).
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat Bovine Expected from Sequence Cat Expected from Sequence Dog Expected from Sequence Horse Expected from Sequence Pig Expected from Sequence Rabbit Expected from Sequence Rhesus Monkey Expected from Sequence Sheep Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Immunogen
- 12 amino acid peptide of the C-terminus of hGLUT-1 (LFHPLGADSQV) conjugated to KLH.
- Approx. Protein Concentrations
- IgG concentration 0.1mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P11166
- Entrez Gene
- SLC2A1
- GO Terms
- GO:0016021 integral to membrane
- GO:0005624 membrane fraction
- GO:0005975 carbohydrate metabolic process
- GO:0006112 energy reserve metabolic process
- GO:0006767 water-soluble vitamin metabolic process
- GO:0050796 regulation of insulin secretion
- GO:0030496 midbody
- GO:0033300 dehydroascorbic acid transporter activity
- GO:0042470 melanosome
- GO:0055056 D-glucose transmembrane transporter activity
- Regulatory
- For research purposes only
Applications of Glucose Transporter 1 antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunoprecipitation | 1 | 10ug/ml | |
Western Blotting | 1 | 10ug/ml |
Secondary Antibodies Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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Sheep anti Rabbit IgG:DyLight®488 | STAR36D488GA | F IF WB | 0.1 mg | ||
Sheep anti Rabbit IgG:DyLight®680 | STAR36D680GA | F IF WB | 0.1 mg | ||
Sheep anti Rabbit IgG:Dylight®800 | STAR36D800GA | F IF WB | 0.1 mg |
Useful Reagents Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml |
Product Specific References
Further Reading
-
Chen, L.Y. & Phelix, C.F. (2019) Extracellular gating of glucose transport through GLUT 1.
Biochem Biophys Res Commun. Feb 26 [Epub ahead of print].
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