Glucagon antibody
Goat anti Human glucagon antibody detects glucagon, a pancreatic hormone whose actions are antagonistic to insulin, functioning to increase blood glucose through stimulation of glycogenolysis and gluconeogenesis in the liver. Glucagon is a ligand for the glucagon receptor, a G-protein linked receptor whose signalling pathway controls cell proliferation.
Glucagon is secreted from A-cells within the Islets of Langerhans in the pancreas.
Glucagon is secreted from A-cells within the Islets of Langerhans in the pancreas.
Product Details
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3) - Immunogen
- Synthetic peptide corresponding to amino acids 8-18 of human glucagon.
- Approx. Protein Concentrations
- IgG concentration 5.0 mg/ml
Storage Information
- Storage
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P01275
- Entrez Gene
- GCG
- GO Terms
- GO:0005886 plasma membrane
- GO:0005576 extracellular region
- GO:0005179 hormone activity
- GO:0005625 soluble fraction
- GO:0006112 energy reserve metabolic process
- GO:0007186 G-protein coupled receptor protein signaling pathway
- GO:0007631 feeding behavior
- GO:0050796 regulation of insulin secretion
- GO:0008283 cell proliferation
- GO:0071377 cellular response to glucagon stimulus
- Regulatory
- For research purposes only
Applications of Glucagon antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | 1/200 | 1/20000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Copyright © 2021 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Rabbit anti Goat IgG (Fc):FITC | STAR122F | F | 1 mg |
|
|
| Rabbit anti Goat IgG (Fc):HRP | STAR122P | C E WB | 1 mg |
|
Product Specific References
Further Reading
-
Woods, S.C. et al. (2006) Pancreatic signals controlling food intake; insulin, glucagon and amylin.
Philos Trans R Soc Lond B Biol Sci. 361 (1471): 1219-35.
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