Goat anti Human glucagon antibody detects glucagon, a pancreatic hormone whose actions are antagonistic to insulin, functioning to increase blood glucose through stimulation of glycogenolysis and gluconeogenesis in the liver. Glucagon is a ligand for the glucagon receptor, a G-protein linked receptor whose signalling pathway controls cell proliferation.
Glucagon is secreted from A-cells within the Islets of Langerhans in the pancreas.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Synthetic peptide corresponding to amino acids 8-18 of human glucagon.
- Approx. Protein Concentrations
- IgG concentration 5.0 mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
energy reserve metabolic process
G-protein coupled receptor protein signaling pathway
regulation of insulin secretion
cellular response to glucagon stimulus
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Glucagon antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
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Secondary Antibodies Available