Glucagon antibody

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Goat anti Human Glucagon

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
4660-1100G E 1 ml
Goat anti Human glucagon antibody detects glucagon, a pancreatic hormone whose actions are antagonistic to insulin, functioning to increase blood glucose through stimulation of glycogenolysis and gluconeogenesis in the liver. Glucagon is a ligand for the glucagon receptor, a G-protein linked receptor whose signalling pathway controls cell proliferation.

Glucagon is secreted from A-cells within the Islets of Langerhans in the pancreas.

Product Details

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09%Sodium Azide (NaN3)
Immunogen
Synthetic peptide corresponding to amino acids 8-18 of human glucagon.
Approx. Protein Concentrations
IgG concentration 5.0 mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P01275 Related reagents
Entrez Gene
GCG Related reagents
GO Terms
GO:0005886 plasma membrane
GO:0005576 extracellular region
GO:0005179 hormone activity
GO:0005625 soluble fraction
GO:0006112 energy reserve metabolic process
GO:0007186 G-protein coupled receptor protein signaling pathway
GO:0007631 feeding behavior
GO:0050796 regulation of insulin secretion
GO:0008283 cell proliferation
GO:0071377 cellular response to glucagon stimulus
Regulatory
For research purposes only

Applications of Glucagon antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/200 1/20000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F 1 mg F
Rabbit anti Goat IgG (Fc):HRP STAR122P 1 mg C E WB

Product Specific References

Further Reading

  1. Woods, S.C. et al. (2006) Pancreatic signals controlling food intake; insulin, glucagon and amylin.
    Philos Trans R Soc Lond B Biol Sci. 361 (1471): 1219-35.