Gelsolin antibody

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Anti Gelsolin Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with gelsolin antibody followed by detection with HRP conjugated Goat anti Rabbit IgG antibody (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 61 second exposure. Arrow points to gelsolin (molecular weight 90 kDa).

Rabbit anti Gelsolin

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: Gelsolin

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VPA00498 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human gelsolin antibody recognizes gelsolin, also known as actin-depolymerizing factor, AGEL or brevin.

The protein encoded by GSN gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in GSN are a cause of familial amyloidosis Finnish type (AMLY5). Multiple transcript variants encoding several different isoforms have been found for GSN (provided by RefSeq, Jul 2008).

Rabbit anti Human gelsolin antibody detects a band of 90 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti gelsolin detects a band of approximately 90 kDa in HeLa cell lysates.
Product Form: Purified IgG - liquid.
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
2% Sucrose.
Immunogen: Synthetic peptide directed towards the C terminal region of human gelsolin
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: P06396
Entrez Gene: GSN
GO Terms: GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0003779 actin binding; GO:0051016 barbed-end actin filament capping; GO:0051014 actin filament severing; GO:0005829 cytosol; GO:0006921 cellular component disassembly involved in apoptosis; GO:0030041 actin filament polymerization; GO:0015629 actin cytoskeleton; View More GO Terms