Gelsolin antibody

Rabbit anti Gelsolin
- Product Type
- PrecisionAb Polyclonal
- Isotype
- Polyclonal IgG
- Format
- Purified
- Specificity
- Gelsolin
Rabbit anti Human gelsolin antibody recognizes gelsolin, also known as actin-depolymerizing factor, AGEL or brevin. The protein encoded by GSN gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in GSN are a cause of familial amyloidosis Finnish type (AMLY5). Multiple transcript variants encoding several different isoforms have been found for GSN (provided by RefSeq, Jul 2008). Rabbit anti Human gelsolin antibody detects a band of 90 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
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- Target Species
- Human
- Western Blotting
- Anti gelsolin detects a band of approximately 90 kDa in HeLa cell lysates.
- Product Form
- Purified IgG - liquid.
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
2% Sucrose. - Immunogen
- Synthetic peptide directed towards the C terminal region of human gelsolin
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | ![]() |
1/1000 |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Goat anti Rabbit IgG (H/L):HRP |
- UniProt
- P06396
- Entrez Gene
- GSN
- GO Terms
- GO:0005515 protein binding
- GO:0005509 calcium ion binding
- GO:0003779 actin binding
- GO:0051016 barbed-end actin filament capping
- GO:0051014 actin filament severing
- GO:0005829 cytosol
- GO:0006921 cellular component disassembly involved in apoptosis
- GO:0030041 actin filament polymerization
- GO:0015629 actin cytoskeleton
- View More GO Terms
VPA00498

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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