GDI1 antibody

Rabbit anti GDI1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
GDI1

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VPA00272
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Rabbit anti Human GDI1 antibody recognizes GDI1, also known as guanosine diphosphate dissociation inhibitor 1, mental retardation, X-linked 48, oligophrenin-2, protein XAP-4, rab GDI alpha and rab GDP-dissociation inhibitor, alpha.

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation (provided by RefSeq, Jul 2008).

Rabbit anti Human GDI1 antibody detects a band of 51 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti GDI1 detects a band of approximately 51 kDa in SH-SY5Y cell lysate.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin.
Immunogen
KLH-conjugated synthetic peptide corresponding to aa 415-443 of human GDI1
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
P31150
Entrez Gene
GDI1
GO Terms
GO:0005515 protein binding
GO:0005829 cytosol
GO:0005096 GTPase activator activity
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0030496 midbody
GO:0043087 regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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