GDI-2 antibody

Rabbit anti GDI-2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
GDI-2

Product Code Applications Pack Size List Price Your Price Qty
AHP2736
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SDS Safety Datasheet SDS
WB 50 µl loader
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Rabbit anti GDI-2 antibody recognizes Rab GDP dissociation inhibitor beta, also known as Rab GDI beta, GDI-2, guanosine diphosphate dissociation inhibitor 2. GDI-2 is a member of a family of chaperone proteins, which control Rho GTPases (DerMardirossian and Bokoch 2005). It has been shown to function as a metastasis suppressor in bladder cancer (Gildea et al. 2002)

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to GDI-2 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
<0.1% Sodium Azide (NaN3)
50% Glycerol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 296-445 of human GDI-2
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/200 1/3000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti GDI-2 antibody detects a band of approximately 51 kDa in various cell and tissue lysates under reducing conditions

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UniProt
P50395
Entrez Gene
GDI2
GO Terms
GO:0005515 protein binding
GO:0016020 membrane
GO:0005829 cytosol
GO:0005093 Rab GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
GO:0007264 small GTPase mediated signal transduction
GO:0009986 cell surface
GO:0015031 protein transport
GO:0043087 regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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