Galectin-3 antibody

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Rabbit anti Galectin-3

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00076
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human galectin-3 antibody recognizes human galectin-3, a member of the galectin family of beta-galactoside-binding proteins which are involved in both intracellular and extracellular functions and exhibit anti-apoptotic properties.

Galectin-3 is implicated in many biological processes, including cell differentiation, growth, adhesion, angiogenesis and inflammation, and is expressed in a wide range of neoplasms. Galectin-3 acts as a regulator of tumor metastasis, and several studies have shown a correlation between levels of galectin-3 and tumor progression in liver, thyroid, colon, gastric and breast carcinomas, making galectin-3 an emerging cancer marker.

Rabbit anti Human galectin-3 antibody detects a single band of 26 kDa in a range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.

Product Details

Target Species
Human
Western Blotting
Rabbit anti galectin-3 detects a band of approximately 26 kDa in MCF7 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Recombinant human galectin-3

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
12 months from date of despatch

More Information

UniProt
P17931
Entrez Gene
LGALS3
GO Terms
GO:0005886 plasma membrane
GO:0005529 sugar binding
GO:0005634 nucleus
GO:0005743 mitochondrial inner membrane
GO:0019863 IgE binding
GO:0030154 cell differentiation
GO:0045087 innate immune response
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of Galectin-3 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml