Galectin-3 antibody
Rabbit anti Human galectin-3 antibody recognizes human galectin-3, a member of the galectin family of beta-galactoside-binding proteins which are involved in both intracellular and extracellular functions and exhibit anti-apoptotic properties.
Galectin-3 is implicated in many biological processes, including cell differentiation, growth, adhesion, angiogenesis and inflammation, and is expressed in a wide range of neoplasms. Galectin-3 acts as a regulator of tumor metastasis, and several studies have shown a correlation between levels of galectin-3 and tumor progression in liver, thyroid, colon, gastric and breast carcinomas, making galectin-3 an emerging cancer marker.
Rabbit anti Human galectin-3 antibody detects a single band of 26 kDa in a range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.
Galectin-3 is implicated in many biological processes, including cell differentiation, growth, adhesion, angiogenesis and inflammation, and is expressed in a wide range of neoplasms. Galectin-3 acts as a regulator of tumor metastasis, and several studies have shown a correlation between levels of galectin-3 and tumor progression in liver, thyroid, colon, gastric and breast carcinomas, making galectin-3 an emerging cancer marker.
Rabbit anti Human galectin-3 antibody detects a single band of 26 kDa in a range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.
Product Details
- Target Species
- Human
- Western Blotting
- Rabbit anti galectin-3 detects a band of approximately 26 kDa in MCF7 cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- Recombinant human galectin-3
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- As supplied, 12 months from date of despatch.
More Information
- UniProt
- P17931 Related reagents
- Entrez Gene
- LGALS3 Related reagents
- GO Terms
- GO:0005886 plasma membrane
- GO:0005529 sugar binding
- GO:0005634 nucleus
- GO:0005743 mitochondrial inner membrane
- GO:0019863 IgE binding
- GO:0030154 cell differentiation
- GO:0045087 innate immune response
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of Galectin-3 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Copyright © 2020 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
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