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FYN (pSer21) antibody

Rabbit anti FYN (pSer21)

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
FYN (pSer21)

Product Code Applications Pack Size List Price Your Price Qty
AHP2621
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 50 µl loader
List Price Your Price
loader

Rabbit anti FYN (pSer21) antibody recognizes FYN, when phosphorylated at serine 21. Fyn is a proto-oncogene tyrosine kinase. Fyn is phosphorylated at serine 21 by Protein Kinase A. Phosphorylation of FYN at serine 21 results in increased phosphorylation of focal adhesion kinase (FAK) and contributes to cellular migration.

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to FYN (pSer21) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Phospho specific-peptide corresponding to residues surrounding serine 21 of human FYN
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
P06241
Entrez Gene
FYN
GO Terms
GO:0005886 plasma membrane
GO:0001948 glycoprotein binding
GO:0005829 cytosol
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0046872 metal ion binding
GO:0005524 ATP binding
GO:0005768 endosome
GO:0006468 protein phosphorylation
GO:0006816 calcium ion transport
GO:0007243 intracellular protein kinase cascade
GO:0007411 axon guidance
GO:0007612 learning
GO:0007631 feeding behavior
GO:0042802 identical protein binding
GO:0016032 viral reproduction
GO:0030168 platelet activation
GO:0031295 T cell costimulation
GO:0044419 interspecies interaction between organisms
GO:0050690 regulation of defense response to virus by virus
GO:0050852 T cell receptor signaling pathway
GO:0050900 leukocyte migration

AHP2621

141579 158624

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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