FUSE-Binding Protein 1 antibody

Rabbit anti FUSE-Binding Protein 1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
FUSE-Binding Protein 1

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VPA00243
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Rabbit anti Human FUSE-binding protein 1 antibody recognizes the far upstream element (FUSE)-binding protein 1, also known as DNA helicase V and hDH V.

Encoded by the FUBP1 gene, FUSE-binding protein 1 is a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase (provided by RefSeq, Jul 2008).

Rabbit anti Human FUSE-binding protein 1 antibody detects a band of 77 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti FUSE-binding protein 1 detects a band of approximately 77 kDa in HepG2 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
KLH conjugated synthetic peptide between 240-268 amino acids from the central region of human FUSE-binding protein 1
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
Q96AE4
Entrez Gene
FUBP1
GO Terms
GO:0005515 protein binding
GO:0003697 single-stranded DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0006366 transcription from RNA polymerase II promoter
GO:0045449 regulation of transcription
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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