Rabbit anti FOXO4 antibody recognizes FOXO4 (forkhead box protein O4) also known as AFX. FOXO4 is a transcription factor that plays a role in insulin signaling and cell cycle regulation.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 30% Glycerol
0.5% Bovine Serum Albumin
- Synthetic peptide surrounding amino acid 491 of human FOXO4
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
G1 phase of mitotic cell cycle
double-stranded DNA binding
specific RNA polymerase II transcription factor activity
sequence-specific enhancer binding RNA polymerase II transcription factor activity
transcription factor complex
cell cycle arrest
mitotic cell cycle G2/M transition DNA damage checkpoint
pattern specification process
muscle organ development
transcription factor binding
negative regulation of cell proliferation
insulin receptor signaling pathway
DNA bending activity
negative regulation of gene-specific transcription from RNA polymerase II promoter
negative regulation of angiogenesis
transcription activator activity
specific transcriptional repressor activity
protein kinase binding
positive regulation of transcription from RNA polymerase II promoter
nerve growth factor receptor signaling pathway
regulation of transcription factor activity
negative regulation of smooth muscle cell differentiation
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of FOXO4 antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti FOXO4 antibody recognizes a band of approximately 60 kDa in 3T3 cell lysates and rat kidney tissue lysates
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Secondary Antibodies Available
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