Rabbit anti FOXO3A antibody recognizes (forkhead box protein O3). The FOXO3A transcription factor plays a role in the onset of apoptosis when survival factors are absent. FOXO3A has also been shown to trigger neuronal damage in response to oxidative stress in addition to playing a role in the post-transcriptional regulation of the myc oncogene.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 30% Glycerol
0.5% Bovine Serum Albumin
- Synthetic peptide corresponding to residues on the C-terminus of human FOXO3A
- Approx. Protein Concentrations
- IgG concentration 0.2 mg/ml
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
ovulation from ovarian follicle
initiation of primordial ovarian follicle growth
antral ovarian follicle growth
double-stranded DNA binding
specific RNA polymerase II transcription factor activity
sequence-specific enhancer binding RNA polymerase II transcription factor activity
transcription factor complex
induction of apoptosis
pattern specification process
transcription factor binding
insulin receptor signaling pathway
DNA bending activity
negative regulation of gene-specific transcription from RNA polymerase II promoter
transcription activator activity
specific transcriptional repressor activity
protein kinase binding
regulation of cell proliferation
positive regulation of erythrocyte differentiation
positive regulation of transcription from RNA polymerase II promoter
nerve growth factor receptor signaling pathway
regulation of transcription factor activity
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of FOXO3A antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti FOXO3A antibody recognizes a band of approximately 75 kDa in Jurkat cell lysates, rat liver tissue lysates and rat kidney tissue lysates
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Secondary Antibodies Available
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