Rabbit anti FOXO3A antibody recognizes human forkhead box, also known as O3A FOXO3A, FKHLR1 and FOXO3, a ~95 kDa member of the forkhead family of transcription factors. FOXO3A is ubiquitously expressed and is an important regulator of apoptosis and the cell cycle.
FOXO3A triggers apoptosis by inducing the expression of genes necessary for cell death.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antisera to Human FOXO3A were raised by repeated immunisation of Rabbits with highly purified antigen Purified IgG prepared from whole serum by affinity chromatography
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3)
- A synthetic peptide corresponding to 18 amino acid sequence from near the amino terminus of human FOXO3A.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
ovulation from ovarian follicle
initiation of primordial ovarian follicle growth
antral ovarian follicle growth
double-stranded DNA binding
specific RNA polymerase II transcription factor activity
sequence-specific enhancer binding RNA polymerase II transcription factor activity
transcription factor complex
induction of apoptosis
pattern specification process
transcription factor binding
insulin receptor signaling pathway
DNA bending activity
negative regulation of gene-specific transcription from RNA polymerase II promoter
transcription activator activity
specific transcriptional repressor activity
protein kinase binding
regulation of cell proliferation
positive regulation of erythrocyte differentiation
positive regulation of transcription from RNA polymerase II promoter
nerve growth factor receptor signaling pathway
regulation of transcription factor activity
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of FOXO3A antibody
|Immunohistology - Frozen
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- This product is suitable for use in indirect ELISA applications.
- Histology Positive Control Tissue
- A-20 cells
- Western Blotting
- AHP2245 detects a band of approximately 96 kDa in A-20 cell lysates.
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Secondary Antibodies Available
Useful Reagents Available