Rabbit anti Human Fibronectin antibody
recognizes human fibronectin (FN)), also known as Cold-insoluble globulin (CIS). Fibronectin is a 2386 amino acid plasma protein containing twelve fibronectin type-I
domains, 2 fibronectin type-II
domains and 16 fibronectin type-III
Soluble fibronectin is mainly synthesized by hepatocytes whilst the less soluble cellular fibronectin is synthesized by a variety of cell types and has a more diverse phenotype due to cell specific post translational modifications (Schwarzbauer 1991
). Fibronectin is a multifunctional molecule bearing a number of cell binding and protein interaction domains
attesting to its role in processes ranging from acting as an integrin ligand through self assembly to heparin and collagen binding anf fibrin interactions during wound repair (Pankov and Yamada 2002
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Approx. Protein Concentrations
- IgG concentration 5.0 mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- Entrez Gene
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Fibronectin antibody
|Immunohistology - Frozen
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
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Secondary Antibodies Available