FGFR3 antibody

Rabbit anti FGFR3

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
FGFR3

Product Code Applications Pack Size List Price Your Price Qty
AHP2453
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 50 µl loader
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Rabbit anti FGFR3 antibody recognizes fibroblast growth factor receptor 3 (FGFR3) also known as CD333.

FGFR3 is a member of the tyrosine protein kinase family and a receptor for fibroblast growth factors. FGFR3 plays an important role in numerous cellular processes such as proliferation, differentiation, migration and survival.

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to FGFR3 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant human FGFR3
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti FGFR3 antibody detects a band of approximately 88 kDa in Jurkat cell lysate under reducing conditions

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Synonyms
CD333
UniProt
P22607
Entrez Gene
FGFR3
GO Terms
GO:0000165 MAPKKK cascade
GO:0016049 cell growth
GO:0005007 fibroblast growth factor receptor activity
GO:0005887 integral to plasma membrane
GO:0005524 ATP binding
GO:0006468 protein phosphorylation
GO:0007259 JAK-STAT cascade
GO:0008284 positive regulation of cell proliferation
GO:0008286 insulin receptor signaling pathway
GO:0042802 identical protein binding
GO:0017134 fibroblast growth factor binding
GO:0048640 negative regulation of developmental growth
GO:0070977 bone maturation
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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