Ezrin antibody
Filter by Application:
WB ResetGoat anti Ezrin
- Product Type
- PrecisionAb Polyclonal
- Isotype
- Polyclonal IgG
- Format
- Purified
- Specificity
- Ezrin
Quick Links:
Antibody Quality and 
Unrivaled 
| Goat anti Human ezrin antibody recognizes human ezrin, otherwise known as p81 or villin 2. Ezrin is a 586 amino acid, cytoplasmic peripheral membrane protein containing a single FERM domain and member of the ezrin, radixin, moesin (ERM) protein family, which acts as protein-tyrosine kinase substrate. Ezrin is enriched in microvilli and other cell surface structures and plays a key role in cell surface structure adhesion, membrane trafficking, motility and organization (Ng et al. 2001). Ezrin acts as a linker protein between the plasma membrane and the actin cytoskeleton, and provides anchorage for cell surface molecules such as ICAM and CD44 (Finnerty et al. 2004). Ezrin is implicated in the metastatic capacity of various types of human tumors including breast, prostate, bone, endometrial and colon cancers (Ohtani et al. 1999, Elzaqheid et al. 2008). Goat anti Human ezrin antibody recognizes human ezrin as a single band of ~80 kDa in multiple human cell line lysates by western blotting under reducing conditions. |
|
- Target Species
- Human
- Western Blotting
- Anti ezrin antibody detects a band of approximately 80 kDa in HeLa cell lysates.
- Product Form
- Purified IgG - liquid
- Preparation
- Goat polyclonal antibody purified by ammonium sulfate precipitation followed by antigen affinity chromatography.
- Buffer Solution
- TRIS buffered saline.
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin - Immunogen
- Peptide sequence C-QDYEEKTKKAER from an internal region of ezrin
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Rabbit anti Goat IgG (Fc):HRP | STAR122P | C E WB | 1 mg |
 |
Log in | ||
| List Price | Your Price | ||||||
|
|
Log in | ||||||
| Description | Rabbit anti Goat IgG (Fc):HRP | ||||||
- Synonyms
- Villin 2
- UniProt
- P15311
- Entrez Gene
- EZR
- GO Terms
- GO:0051015 actin filament binding
- GO:0051017 actin filament bundle assembly
- GO:0050839 cell adhesion molecule binding
- GO:0005829 cytosol
- GO:0005730 nucleolus
- GO:0005884 actin filament
- GO:0007016 cytoskeletal anchoring at plasma membrane
- GO:0007159 leukocyte cell-cell adhesion
- GO:0007411 axon guidance
- View More GO Terms
- GO:0008360 regulation of cell shape
- GO:0016324 apical plasma membrane
- GO:0019898 extrinsic to membrane
- GO:0022614 membrane to membrane docking
- GO:0030175 filopodium
- GO:0030863 cortical cytoskeleton
- GO:0031528 microvillus membrane
- GO:0032587 ruffle membrane
View more products with EZRIN specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
View all Anti-Human ProductsAlways be the first to know.
When we launch new products and resources to help you achieve more in the lab.
Yes, sign me up