Ezrin antibody

ISO 9001 Quality Assurance Manufacturing | Print

Anti Ezrin Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with ezrin antibody followed by detection with HRP conjugated Rabbit anti Goat IgG (Fc) (1/10,000, STAR122P) and visualized on the ChemiDoc MP with 29 second exposure. Arrow points to ezrin (molecular weight 80 kDa)

Filter by Application:

Goat anti Ezrin

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: Ezrin

Quick Links:

Secondary Antibodies
Applications
Storage Information
Batch/Lot Specific Datasheets

Antibody Quality and Performance Guarantee

Unrivaled Technical Support

Product Code Applications Pack Size List Price Your Price Qty

List Price	Your Price
VPA00029 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
	Log in

Goat anti Human ezrin antibody recognizes human ezrin, otherwise known as p81 or villin 2. Ezrin is a 586 amino acid, cytoplasmic peripheral membrane protein containing a single FERM domain and member of the ezrin, radixin, moesin (ERM) protein family, which acts as protein-tyrosine kinase substrate.

Ezrin is enriched in microvilli and other cell surface structures and plays a key role in cell surface structure adhesion, membrane trafficking, motility and organization (Ng et al. 2001). Ezrin acts as a linker protein between the plasma membrane and the actin cytoskeleton, and provides anchorage for cell surface molecules such as ICAM and CD44 (Finnerty et al. 2004). Ezrin is implicated in the metastatic capacity of various types of human tumors including breast, prostate, bone, endometrial and colon cancers (Ohtani et al. 1999, Elzaqheid et al. 2008).

Goat anti Human ezrin antibody recognizes human ezrin as a single band of ~80 kDa in multiple human cell line lysates by western blotting under reducing conditions.

Target Species: Human
Western Blotting: Anti ezrin antibody detects a band of approximately 80 kDa in HeLa cell lysates.
Product Form: Purified IgG - liquid
Preparation: Goat polyclonal antibody purified by ammonium sulfate precipitation followed by antigen affinity chromatography.
Buffer Solution: TRIS buffered saline.
Preservative Stabilisers: 0.02% Sodium Azide (NaN₃)
0.5% Bovine Serum Albumin
Immunogen: Peptide sequence C-QDYEEKTKKAER from an internal region of ezrin
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Rabbit anti Goat IgG (Fc):HRP	STAR122P	C E WB	1 mg	Log in	Get Quote
List Price	Your Price
	Log in
Description	Rabbit anti Goat IgG (Fc):HRP

Synonyms: Villin 2
UniProt: P15311
Entrez Gene: EZR
GO Terms: GO:0051015 actin filament binding; GO:0051017 actin filament bundle assembly; GO:0050839 cell adhesion molecule binding; GO:0005829 cytosol; GO:0005730 nucleolus; GO:0005884 actin filament; GO:0007016 cytoskeletal anchoring at plasma membrane; GO:0007159 leukocyte cell-cell adhesion; GO:0007411 axon guidance; View More GO Terms; GO:0008360 regulation of cell shape; GO:0016324 apical plasma membrane; GO:0019898 extrinsic to membrane; GO:0022614 membrane to membrane docking; GO:0030175 filopodium; GO:0030863 cortical cytoskeleton; GO:0031528 microvillus membrane; GO:0032587 ruffle membrane