ETS1 antibody

Rabbit anti ETS1

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
ETS1

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AHP2463
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Rabbit anti ETS1 antibody recognizes EST1, also known as p54. ETS1 belongs to the ETS family of transcription factors. Members of the ETS bind a particular motif that contains the sequence GGAA/T as a core element.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse Expected from Sequence
Rat Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to ETS1 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant human ETS1
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/50 1/200
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti ETS1 antibody detects a band of approximately 55 kDa in cell lysates under reducing conditions

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UniProt
P14921
Entrez Gene
ETS1
GO Terms
GO:0005515 protein binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003702 RNA polymerase II transcription factor activity
GO:0005634 nucleus
GO:0006366 transcription from RNA polymerase II promoter
GO:0006917 induction of apoptosis
GO:0006955 immune response
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell proliferation
GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
GO:0046677 response to antibiotic
GO:0030578 PML body organization
GO:0043565 sequence-specific DNA binding
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045786 negative regulation of cell cycle
GO:0045941 positive regulation of transcription
GO:0048870 cell motility
GO:0051272 positive regulation of cellular component movement
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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