ERLIN-2 antibody

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Rabbit anti ERLIN-2

Rabbit anti-human Erlin-2 antibody recognizes Erlin-2, also known as SPFH domain family, member 2, endoplasmic reticulum lipid raft-associated protein 2 or stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2.

Product Type
PrecisionAb™ Polyclonal
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
VPA00592 WB 100 µl
Rabbit anti Human erlin-2 antibody recognizes erlin-2, also known as SPFH domain family, member 2, endoplasmic reticulum lipid raft-associated protein 2 or stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2.

The ERLIN2 gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is a 339 amino acid ~43 kDa single pass type II transmembrane protein localized to lipid rafts of the endoplasmic reticulum membrane and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in ERLIN2 are a cause of Spastic paraplegia 18, autosomal recessive (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for ERLIN2 (provided by RefSeq, Feb 2012).

Rabbit anti Human erlin-2 antibody detects a band of 43 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Western Blotting
Anti erlin-2 detects a band of approximately 43 kDa in HEK293 cell lysates.
Product Form
Purified IgG - liquid.
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
2% Sucrose.
Synthetic peptide directed towards the middle region of human erlin-2
Instructions For Use
Please refer to the PrecisionAb western blotting protocol.

Storage Information

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
As supplied, 12 months from date of despatch.

More Information

O94905 Related reagents
Entrez Gene
ERLIN2 Related reagents
GO Terms
GO:0005886 plasma membrane
GO:0005515 protein binding
GO:0016021 integral to membrane
GO:0005789 endoplasmic reticulum membrane
GO:0030433 ER-associated protein catabolic process
PrecisionAb™ is a trademark of Bio-Rad Laboratories.
For research purposes only.

Applications of ERLIN-2 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P 2 ml WB
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