ErbB4 (pTyr1284) antibody
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Filter by Application:
WB ResetRabbit anti ErbB4 (pTyr1284)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Format
- Purified
- Specificity
- ErbB4 (pTyr1284)
Antibody Quality and 
Unrivaled 
| Rabbit anti ErbB4 (pTyr1284) antibody recognizes ErbB4, also known as receptor tyrosine-protein kinase erbB-4 or tyrosine kinase-type cell surface receptor HER4, when phosphorylated at tyrosine 1284. ErbB4 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases and plays a key role in the regulation of the nervous system, heart and mammary gland. Tyrosine 1284 of ErbB4 has been identified as a phosphorylation site (Kaushansky et al. 2008). |
|
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Expected from Sequence Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to ErbB4 (pTyr1284) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
50% Glycerol - Immunogen
- Phospho specific-peptide corresponding to residues surrounding tyrosine 1284 of human ErbB4
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/500 | 1/2000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Further Reading
-
Kaushansky, A. et al. (2008) System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties.
Chem Biol. 15 (8): 808-17.
- UniProt
- Q15303
- Entrez Gene
- ERBB4
- GO Terms
- GO:0005515 protein binding
- GO:0016021 integral to membrane
- GO:0004714 transmembrane receptor protein tyrosine kinase activity
- GO:0004716 receptor signaling protein tyrosine kinase activity
- GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
- GO:0005524 ATP binding
- GO:0005634 nucleus
- GO:0005737 cytoplasm
- GO:0006350 transcription
- View More GO Terms
- GO:0006468 protein phosphorylation
- GO:0008283 cell proliferation
- GO:0016323 basolateral plasma membrane
- GO:0045449 regulation of transcription
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