Eotaxin 2 antibody

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Goat anti Human Eotaxin 2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
AHP1030 E FN WB 0.1 mg
Goat anti Human Eotaxin 2 antibody recognizes human Eotaxin 2, otherwise known as CCL24 and myeloid progenitor inhibitory factor 2 (MPIF-2), an eosinophil-specific chemokine which signals through the CCR3 receptor and is expressed principally by the jejunum and spleen, and to a lesser extent by the lungs and liver. Expression of Eotaxin 2 is induced by allergen challenge.

Product Details

Target Species
Human
Product Form
Purified IgG - lyophilised
Reconstitution
Reconstitute with 0.1ml distilled water.
For long term storage the addition of 0.09% sodium azide is recommended.
N.B. For functional studies do not add azide.
Antiserum Preparation
Antisera to human Eotaxin 2 were raised by repeated immunisations of goats with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
None present.
Immunogen
Recombinant human Eotaxin-2.
Approx. Protein Concentrations
IgG concentration 1.0mg/ml

Storage Information

Storage
Prior to reconstitution store at +4oC.
After reconstitution store at -20oC.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
12 months from date of reconstitution.

More Information

UniProt
O00175 Related reagents
Entrez Gene
CCL24 Related reagents
GO Terms
GO:0001938 positive regulation of endothelial cell proliferation
GO:0007165 signal transduction
GO:0005615 extracellular space
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007267 cell-cell signaling
GO:0008009 chemokine activity
GO:0030335 positive regulation of cell migration
GO:0030838 positive regulation of actin filament polymerization
GO:0032855 positive regulation of Rac GTPase activity
Regulatory
For research purposes only

Applications of Eotaxin 2 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 0.5ug/ml
Functional Assays 4.0 6.0ug/ml
Western Blotting 0.1 0.2ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F 1 mg F
Rabbit anti Goat IgG (Fc):HRP STAR122P 1 mg C E WB

Product Specific References

References for Eotaxin 2 antibody

  1. Fiorucci, G. et al. (2007) Microarray analysis reveals CCL24/eotaxin-2 as an effector of the pathogenetic effects induced by HIV-1 Nef.
    Curr Drug Discov Technol. 4 (1): 12-23.

Further Reading

  1. Patel, V.P. et al. (1997) Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors.
    J Exp Med. 185 (7): 1163-72.