Endophilin B1 antibody

Rabbit anti Endophilin B1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
Endophilin B1

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VPA00401
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Rabbit anti Human endophilin B1 antibody recognizes endophilin B1, also known as Bax-interacting factor 1 or PPP1R70.

Endophilin B1 is a SRC homology 3 domain-containing protein. This protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. It may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants (provided by RefSeq, Sep 2011).

Rabbit anti Human Endophilin B1 antibody detects a band of 42 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti endophilin B1 detects a band of approximately 42 kDa in C2C12 cell lysate.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
KLH-conjugated synthetic peptide corresponding to aa 59-86 of human endophilin B1
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
Q9Y371
Entrez Gene
SH3GLB1
GO Terms
GO:0000139 Golgi membrane
GO:0006915 apoptosis
GO:0007165 signal transduction
GO:0005741 mitochondrial outer membrane
GO:0008289 lipid binding
GO:0006916 anti-apoptosis
GO:0008093 cytoskeletal adaptor activity
GO:0017124 SH3 domain binding
GO:0042803 protein homodimerization activity
GO:0046847 filopodium assembly
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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