Elongin C antibody

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Chicken anti Human Elongin C

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
AHP1830 WB 0.1 mg
Chicken anti Human Elongin C antibody recognizes human Elongin C (EloC), otherwise known as transcription elongation factor B polypeptide 1, a general transcription elongation factor, which stimulates RNA polymerase II transcription elongation beyond template-encoded arresting sites.

Elongin exists as a heterotrimer consisting of an A (A1, A2 or A3), B and C subunit. Subunit A is transcriptionally active, with activity strongly enhanced by binding to the dimeric complex of the elongin regulatory subunits B and C (elongin BC complex), which is mediated by subunit C.

Product Details

Target Species
Human
Product Form
Purified IgY fraction - liquid
Antiserum Preparation
Antiserum to human Elongin C was raised by repeated immunisation of chickens with highly purified antigen.
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Human GST-Elongin C fusion protein.
Purity
>98% IgY purity with no contaminants detected by SDS-PAGE, IEP or RID.
Approx. Protein Concentrations
IgY concentration 17.0mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
Q15369 Related reagents
Entrez Gene
TCEB1 Related reagents
GO Terms
GO:0005515 protein binding
GO:0005829 cytosol
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016032 viral reproduction
GO:0044419 interspecies interaction between organisms
GO:0050434 positive regulation of viral transcription
Regulatory
For research purposes only

Applications of Elongin C antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.