DR3 antibody


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WB IC ResetRabbit anti Human DR3 (Ed)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- DR3
- Region
- (ED)
Rabbit anti Human DR3 recognizes death receptor 3. DR3 is a cell surface receptor containing a death domain, with functional similarities to TNFR1 and Fas/CD95 (Chinnaiyan et al. 1996). The receptor for DR3 is also known as Apo-3L (Marsters et al. 1998), Wsl-1, Apo-3, TRAMP and LARD. DR3 is an inducer of apoptosis and NF-KB activation (Sheikh and Huang 2003). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to DR3 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.02% Sodium Azide - Immunogen
- Peptide from extracellular domain of human DR3.
- Approx. Protein Concentrations
- IgG concentration 1mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Frozen | ![]() |
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Western Blotting 1 | ![]() |
1.0 | 5.0ug/ml |
- 1This product detects a band of approximately 59kDa under both reducing and denaturing conditions.
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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Description | Sheep anti Rabbit IgG:FITC | ||||||
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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Description | Sheep anti Rabbit IgG:RPE |
Further Reading
-
Chinnaiyan, A.M. et al. (1996) Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95.
Science. 274 (5289): 990-2. -
Marsters, S.A. et al. (1998) Identification of a ligand for the death-domain-containing receptor Apo3.
Curr Biol. 8 (9): 525-8.
AHP437



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