Decorin antibody

Sheep anti Human Decorin
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- Decorin
Sheep anti human decorin antibody recognizes the C-terminal region of human bone proteoglycan II, also known as decorin, PG-S2 or PG40. Mutations in the decorin gene are associated with congenital stromal dystrophy of the cornea (CSCD), a rare autosomal dominant eye disease characterized by bilateral corneal clouding (Bredrup et al., 2005). Decorin is involved in autophagy of endothelial cells (Buraschi et al., 2013). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Bovine Chicken - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- Synthetic peptide, CVYVRSAIQLGNYK, corresponding to the C-terminal sequence of human decorin conjugated to Keyhole Limpet Haemocyanin.
- Approx. Protein Concentrations
- IgG concentration 5.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
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Western Blotting | ![]() |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
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Rabbit anti Sheep IgG (H/L):Biotin | 5184-2304 | C E F WB | 1.5 ml |
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Description | Rabbit anti Sheep IgG (H/L):Biotin | ||||||
Donkey anti Sheep/Goat IgG:DyLight®488 | STAR88D488GA | F IF | 0.1 mg |
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Description | Donkey anti Sheep/Goat IgG:DyLight®488 | ||||||
Donkey anti Sheep/Goat IgG:HRP | STAR88P | C E P WB | 1 ml |
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Description | Donkey anti Sheep/Goat IgG:HRP |
Further Reading
-
Bredrup, C. et al. (2005) Congenital stromal dystrophy of the cornea caused by a mutation in the decorin gene.
Invest Ophthalmol Vis Sci. 46: 420-6. -
Buraschi, S. et al. (2013) Decorin causes autophagy in endothelial cells via Peg3.
Proc Natl Acad Sci U S A. 110: E2582-91
- Synonyms
- Bone Proteoglycan II
- RRID
- AB_2169109
- UniProt
- P07585
- Entrez Gene
- DCN
- GO Terms
- GO:0005578 proteinaceous extracellular matrix
- GO:0005615 extracellular space
- GO:0009887 organ morphogenesis
7870-6190

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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