Sheep anti human decorin antibody
recognizes the C-terminal region of human bone proteoglycan II, also known as decorin, PG-S2 or PG40. Mutations in the decorin gene are associated with congenital stromal dystrophy of the cornea (CSCD
), a rare autosomal dominant eye disease characterized by bilateral corneal clouding (Bredrup et al., 2005
). Decorin is involved in autophagy of endothelial cells (Buraschi et al., 2013
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Synthetic peptide, CVYVRSAIQLGNYK, corresponding to the C-terminal sequence of human decorin conjugated to Keyhole Limpet Haemocyanin.
- Approx. Protein Concentrations
- IgG concentration 5.0 mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- Entrez Gene
- GO Terms
proteinaceous extracellular matrix
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Decorin antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
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Secondary Antibodies Available