DDX41 antibody

Goat anti DDX41

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
DDX41

Product Code Applications Pack Size List Price Your Price Qty
AHP3024
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
P WB 0.1 mg
List Price Your Price
Search for Batch Specific Datasheets

Goat anti DDX41 antibody recognizes probable ATP-dependent RNA helicase DDX41, also known as DEAD box protein 41 and ABS.

DDX41 is a helicase and a member of the DEAD-box family of proteins. It functions through the STING-TBK1-IRF3 pathway during innate immunity (Jiang et al. 2017) and is an important sensor of DNA viruses including HSV-1 and adenovirus, directly binding to DNA and STING via its DEADc domain (Zhang et al. 2011). DDX41 has been associated with hematological malignancies, with mutations in DDX41 identified in patients with myeloid neoplasms (Peters et al. 2017).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to human DDX41 were raised by repeated immunizations of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
0.02% Sodium Azide
0.5% Bovine Serum Albumin
Immunogen
Peptide with sequence C-QEERTKAIEAFRE, from the internal region of the protein sequence according to NP_057306.2
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20°C only.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 5 ug/ml
Western Blotting 0.5 ug/ml 2 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Goat anti Human DDX41 antibody detects a band of approximately 85 kDa in cell lysates

Description Product Code Applications Pack Size List Price Your Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F F 1 mg loader
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loader
Description Rabbit anti Goat IgG (Fc):FITC
Rabbit anti Goat IgG (Fc):HRP STAR122P C E WB 1 mg loader
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loader
Description Rabbit anti Goat IgG (Fc):HRP

UniProt
Q9UJV9
Entrez Gene
DDX41
GO Terms
GO:0005515 protein binding
GO:0003723 RNA binding
GO:0006915 apoptosis
GO:0005524 ATP binding
GO:0005681 spliceosomal complex
GO:0006397 mRNA processing
GO:0007275 multicellular organismal development
GO:0008026 ATP-dependent helicase activity
GO:0008380 RNA splicing
GO:0008270 zinc ion binding
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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