DCTN1 antibody
Goat anti Human DCTN1 antibody recognizes DCTN1, the largest component of the dynactin complex. The dynactin complex, via DCTN1, regulates the microtubule-based molecular motor complex, dynein. Through this interaction DCTN1 plays a role in ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis.
Goat anti Human DCTN1 antibody detects DCTN1 as a band of 150 kDa in a wide rangle of human cell lysates. Cross reactivity with rodent cell lines is also observed.
Goat anti Human DCTN1 antibody detects DCTN1 as a band of 150 kDa in a wide rangle of human cell lysates. Cross reactivity with rodent cell lines is also observed.
Product Details
- Target Species
- Human
- Western Blotting
- Goat anti DCTN1 detects a band of approximately 150 kDa in Jurkat cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Goat polyclonal antibody purified by affinity chromatography
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin - Immunogen
- Synthetic peptide sequence C-QEQLHQLHSRLI from the C-terminal region of DCTN1.
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q14203
- Entrez Gene
- DCTN1
- GO Terms
- GO:0000086 G2/M transition of mitotic cell cycle
- GO:0005515 protein binding
- GO:0000776 kinetochore
- GO:0000922 spindle pole
- GO:0003774 motor activity
- GO:0005829 cytosol
- GO:0005874 microtubule
- GO:0007067 mitosis
- GO:0007399 nervous system development
- GO:0008219 cell death
- GO:0030286 dynein complex
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of DCTN1 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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