DCTN1 antibody

Goat anti DCTN1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
DCTN1

Product Code Applications Pack Size List Price Your Price Qty
VPA00065
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl
List Price Your Price
Search for Batch Specific Datasheets

Goat anti Human DCTN1 antibody recognizes DCTN1, the largest component of the dynactin complex. The dynactin complex, via DCTN1, regulates the microtubule-based molecular motor complex, dynein. Through this interaction DCTN1 plays a role in ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis.

Goat anti Human DCTN1 antibody detects DCTN1 as a band of 150 kDa in a wide rangle of human cell lysates. Cross reactivity with rodent cell lines is also observed.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Goat anti DCTN1 detects a band of approximately 150 kDa in Jurkat cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Goat polyclonal antibody purified by affinity chromatography.
Buffer Solution
TRIS buffered saline.
Preservative Stabilisers
0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
Immunogen
Synthetic peptide sequence C-QEQLHQLHSRLI from the C-terminal region of DCTN1.
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Synonyms
DAP-150
UniProt
Q14203
Entrez Gene
DCTN1
GO Terms
GO:0000086 G2/M transition of mitotic cell cycle
GO:0005515 protein binding
GO:0000776 kinetochore
GO:0000922 spindle pole
GO:0003774 motor activity
GO:0005829 cytosol
GO:0005874 microtubule
GO:0007067 mitosis
GO:0007399 nervous system development
GO:0008219 cell death
GO:0030286 dynein complex
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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