Cytochrome P450 1B1 antibody
Rabbit anti Cytochrome P450 1B1
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- Cytochrome P450 1B1
Antibody Quality and Performance Guarantee
| Rabbit anti cytochrome P450 1B1 antibody recognizes cytochrome P450 1B1, also known as CYPIB1. It is a member of the cytochrome P450 superfamily of enzymes. It catalyses the hydroxylation of 17-β-oestradiol at the C4 position (Jefcoate et al. 2000, Potter et al. 2002). A number of Cytochrome P450 1B1 mutations are associated with primary congenital glaucoma (Rauf et al. 2016). |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to cytochrome P450 1B1 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
50% Glycerol - Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human cytochrome P450 1B1
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunofluorescence |  |
1/50 | 1/200 |
| Western Blotting | |
1/500 | 1/2000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti cytochrome P450 1B1 antibody detects a band of approximately 62 kDa in various cell and tissue lysates under reducing conditions
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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| List Price | Your Price | ||||||
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| Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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| List Price | Your Price | ||||||
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| Description | Sheep anti Rabbit IgG:RPE | ||||||
- UniProt
- Q16678
- Entrez Gene
- CYP1B1
- GO Terms
- GO:0009055 electron carrier activity
- GO:0005515 protein binding
- GO:0005789 endoplasmic reticulum membrane
- GO:0005792 microsome
- GO:0055114 oxidation-reduction process
- GO:0006805 xenobiotic metabolic process
- GO:0007601 visual perception
- GO:0019825 oxygen binding
- GO:0020037 heme binding
- View More GO Terms
- GO:0070330 aromatase activity
AHP2731
148744
166792
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
View more products with CYTOCHROME P450 specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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