Cytochrome P450 1A1 antibody
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WB ResetRabbit anti Cytochrome P450 1A1
- Product Type
- PrecisionAb Polyclonal
- Isotype
- Polyclonal IgG
- Format
- Purified
- Specificity
- Cytochrome P450 1A1
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| Rabbit anti Human cytochrome P450 1A1 antibody recognizes CYP1A1, also known as AHRR, aryl hydrocarbon hydroxylase, dioxin-inducible cytochrome P450 1A1, flavoprotein-linked monooxygenase or xenobiotic monooxygenase. The CYP1A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15 (provided by RefSeq, Jul 2008). Rabbit anti Human cytochrome P450 1A1 antibody detects a band of 58 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
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- Target Species
- Human
- Western Blotting
- Rabbit anti cytochrome P450 1A1 detects a band of approximately 58 kDa in HEK293 cell lysates.
- Product Form
- Purified IgG - liquid.
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide
2% Sucrose - Immunogen
- Synthetic peptide encompassing part of the middle region of human cytochrome P450 1A1
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml | Log in | |||
| List Price | Your Price | ||||||
| Log in | |||||||
| Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
- UniProt
- P04798
- Entrez Gene
- CYP1A1
- GO Terms
- GO:0009055 electron carrier activity
- GO:0005789 endoplasmic reticulum membrane
- GO:0005792 microsome
- GO:0055114 oxidation-reduction process
- GO:0019825 oxygen binding
- GO:0017144 drug metabolic process
- GO:0020037 heme binding
- GO:0042359 vitamin D metabolic process
- GO:0070330 aromatase activity
- View More GO Terms
- GO:0070576 vitamin D 24-hydroxylase activity
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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