CTBP1 antibody

Rabbit anti CTBP1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
CTBP1

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VPA00207
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Rabbit anti Human CTBP1 antibody recognizes C-terminal-binding protein 1 (CTBP1), also known as brefeldin A-ribosylated substrate.

Encoded by the CTBP1 gene, C-terminal-binding protein 1 binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. C-terminal-binding protein 1 and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from CTBP1 results in multiple transcript variants (provided by RefSeq, Jul 2008).

Rabbit anti Human CTBP1 antibody detects a band of 47 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti CTBP1 detects a band of approximately 47 kDa in HepG2 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
KLH conjugated synthetic peptide between 413-440 amino acids from the C-terminal region of human CTBP1
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
Q13363
Entrez Gene
CTBP1
GO Terms
GO:0005737 cytoplasm
GO:0055114 oxidation-reduction process
GO:0006468 protein phosphorylation
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0019079 viral genome replication
GO:0008285 negative regulation of cell proliferation
GO:0016564 transcription repressor activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0017053 transcriptional repressor complex
GO:0019904 protein domain specific binding
GO:0044419 interspecies interaction between organisms
GO:0050872 white fat cell differentiation
GO:0051287 NAD binding
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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