CTBP1 antibody

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Rabbit anti CTBP1

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
AHP1583 IF IP WB 0.1 mg
Rabbit anti CtBP1 antibody recognises CtBP1, also known as C-terminal binding protein 1. CtBP1 is a ~49 kDa highly conserved phosphoprotein, originally identified through interaction with the C-terminal portion of adenovirus E1A protein, which primarily acts as a transcriptional corepressor and regulator of target gene transcription, throughout development and malignant transformation.

Rabbit anti CtBP1 antibody (AHP1583) is suitable for use in immunofluorescence studies on cells using acetone/methanol fixation.

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human CtBP1 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Recombinant human CtBP1 expressed in bacteria.
Approx. Protein Concentrations
IgG concentration 1.0mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
Q13363 Related reagents
Entrez Gene
CTBP1 Related reagents
GO Terms
GO:0005737 cytoplasm
GO:0055114 oxidation-reduction process
GO:0006468 protein phosphorylation
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0019079 viral genome replication
GO:0008285 negative regulation of cell proliferation
GO:0016564 transcription repressor activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0017053 transcriptional repressor complex
GO:0019904 protein domain specific binding
GO:0044419 interspecies interaction between organisms
GO:0050872 white fat cell differentiation
GO:0051287 NAD binding
Regulatory
For research purposes only

Applications of CTBP1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunofluorescence 1.0ug/ml
Immunoprecipitation
Western Blotting
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Sheep anti Rabbit IgG:Biotin 2AB02B 1 ml C E P WB
Goat anti Rabbit IgG (Fc):Biotin STAR121B 1 mg E WB
Goat anti Rabbit IgG (Fc):FITC STAR121F 1 mg F
Goat anti Rabbit IgG (Fc):HRP STAR121P 1 mg E WB
Goat anti Rabbit IgG (H/L):HRP STAR124P 1 mg C E WB
Sheep anti Rabbit IgG:FITC STAR34B 1 mg C F
Sheep anti Rabbit IgG:RPE STAR35A 1 ml F
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:DyLight®549 STAR36D549GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®649 STAR36D649GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA 0.1 mg F IF WB

Useful Reagents Available

Description Product Code Pack Size Applications List Price Quantity
TidyBlot™ Western Blot Detection Reagent:HRP STAR209P 0.5 ml WB*

Product Specific References

References for CTBP1 antibody

  1. Valenta, T. et al. (2006) HIC1 attenuates Wnt signaling by recruitment of TCF-4 and Beta-catenin to the nuclear bodies.
    EMBO J. 25: 2326-2337.