Filter by Application:P WB Reset
|Goat anti Human CSK antibody recognizes an epitope within the C-terminal (CT) region of CSK, also known as c-src tyrosine kinase, Tyrosine-protein kinase CSK, p50CSK or Protein-tyrosine kinase CYL. CSK is a cytoplasmic tyrosine kinase ubiquitously expressed as two mRNA species (Partanen et al. 1991), which down-regulates the activity of the c-src oncoprotein (Chong et al. 2005).
CSK is expressed in lung tissues and by macrophages and is highly conserved across species suggesting a role in important regulatory functions (Bräuninger et al. 1992).
- Target Species
- Species Cross-Reactivity
Target Species Cross Reactivity Rat Mouse
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to human CSK (CT) were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
<0.1% Sodium Azide (NaN3) 0.5% Bovine Serum Albumin
- Peptide sequence EQLEHIKTHELHL corresponding to the C-terminal region of CSK (NP_004374.1).
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Paraffin 1||0.1ug/ml||0.3ug/ml|
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.
TRIS/EDTA buffer pH 9.0 is recommended for this purpose.
- Histology Positive Control Tissue
- Human Tonsil
- Western Blotting
- AHP733 detects a band of approximately 50kDa in Jurkat cell lysates.
|Description||Product Code||Applications||Pack Size||List Price||Your Price||Quantity|
|Rabbit anti Goat IgG (Fc):HRP||STAR122P||C E WB||1 mg||Log in|
|List Price||Your Price|
|Description||Rabbit anti Goat IgG (Fc):HRP|
|Rabbit anti Goat IgG (Fc):FITC||STAR122F||F||1 mg||Log in|
|List Price||Your Price|
|Description||Rabbit anti Goat IgG (Fc):FITC|
- Entrez Gene
- GO Terms
- GO:0007596 blood coagulation
- GO:0005829 cytosol
- GO:0004715 non-membrane spanning protein tyrosine kinase activity
- GO:0005524 ATP binding
- GO:0005794 Golgi apparatus
- GO:0005813 centrosome
- GO:0006468 protein phosphorylation
- GO:0007173 epidermal growth factor receptor signaling pathway
- GO:0008022 protein C-terminus binding
- View More GO Terms
- GO:0031295 T cell costimulation
- GO:0050852 T cell receptor signaling pathway
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