CREB3L1 antibody

Rabbit anti CREB3L1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
CREB3L1

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VPA00260
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Rabbit anti Human CREB3L1 antibody recognizes CREB3L1, also known as BBF-2 homolog, cAMP-responsive element-binding protein 3-like protein 1 and old astrocyte specifically-induced substance.

The protein encoded by the CREB3L1 gene is normally found in the membrane of the endoplasmic reticulum (ER). However, upon stress to the ER, the encoded protein is cleaved and the released cytoplasmic transcription factor domain translocates to the nucleus. There it activates the transcription of target genes by binding to box-B elements (provided by RefSeq, Jun 2013).

Rabbit anti Human CREB3L1 antibody detects a band of 57 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti CREB3L1 detects a band of approximately 57 kDa in MOLT-4 cell lysate
Product Form
Ig fraction - liquid
Preparation
Rabbit Ig fraction prepared by ammonium sulphate precipitation
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
KLH-conjugated synthetic peptide corresponding to aa 481-509 of human CREB3L1
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20oC, avoiding repeated freeze thaw cycles

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
Q96BA8
Entrez Gene
CREB3L1
GO Terms
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0006986 response to unfolded protein
GO:0016021 integral to membrane
GO:0005634 nucleus
GO:0005789 endoplasmic reticulum membrane
GO:0006355 regulation of transcription, DNA-dependent
GO:0043565 sequence-specific DNA binding
GO:0046983 protein dimerization activity
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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