CREB1 antibody

Rabbit anti CREB1

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
CREB1

Product Code Applications Pack Size List Price Your Price Qty
AHP2738
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 50 µl loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Rabbit anti CREB1 antibody recognizes cyclin AMP-responsive element-binding protein 1, also known as CREB-1. It belongs to the family of transcription factors mediating gene expression in neuronal and non-neuronal cells (Lonze et al. 2002). CREB1 is activated in response to growth factor stimulation, electrical stimulation and synaptic activity (Shaywitz and Greenberg 1999). In mice, disruption of CREB1 function results in neurodegeneration (Mantamadiotis et al. 2002). CREB1 is overexpressed in gliomas and promotes gliomagenesis acting as a modulator of oncogenic microRNA-23a (Tan et al. 2012). CREB1, together with SETD2, contribute to cisplatin cytotoxicity regulating the ERK signalling pathway (Kim et al. 2018).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to CREB1 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human CREB1
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/3000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti CREB1 antibody detects a band of approximately 40 kDa in various cell ant tissue lysates under reducing conditions

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):Biotin
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):FITC
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):HRP
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (H/L):HRP
Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
List Price Your Price
loader
Description Sheep anti Rabbit IgG:FITC
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
List Price Your Price
loader
Description Sheep anti Rabbit IgG:RPE

UniProt
P16220
Entrez Gene
CREB1
GO Terms
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0002756 MyD88-independent toll-like receptor signaling pathway
GO:0003712 transcription cofactor activity
GO:0006468 protein phosphorylation
GO:0007202 activation of phospholipase C activity
GO:0007268 synaptic transmission
GO:0007411 axon guidance
GO:0008063 Toll signaling pathway
GO:0010033 response to organic substance
GO:0048015 phosphatidylinositol-mediated signaling
GO:0034130 toll-like receptor 1 signaling pathway
GO:0034134 toll-like receptor 2 signaling pathway
GO:0034138 toll-like receptor 3 signaling pathway
GO:0034142 toll-like receptor 4 signaling pathway
GO:0044419 interspecies interaction between organisms
GO:0045087 innate immune response
GO:0046983 protein dimerization activity
GO:0048011 nerve growth factor receptor signaling pathway
GO:0051403 stress-activated MAPK cascade
View more products with CREB1 specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products