CPSF6 antibody

Rabbit anti CPSF6

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
CPSF6

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VPA00710
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Rabbit anti Human CPSF6 antibody recognizes the cleavage and polyadenylation specificity factor subunit 6, also known as CPSF 68 kDa subunit, cleavage and polyadenylation specificity factor 68 kDa subunit, cleavage factor Im complex 68 kDa subunit, or pre-mRNA cleavage factor Im 68 kDa subunit.

The protein encoded by CPSF6 gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. CPSF6 encodes the 68 kDa subunit. It has a domain organization reminiscent of spliceosomal proteins (provided by RefSeq, Jul 2008).

Rabbit anti Human CPSF6 antibody detects a band of 70 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Rabbit anti CPSF6 detects a band of approximately 70 kDa in Jurkat cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography on Protein A.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide
2% Sucrose
Immunogen
Synthetic peptide encompassing part of the middle region of human CPSF6
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
Q16630
Entrez Gene
CPSF6
GO Terms
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0003723 RNA binding
GO:0030529 ribonucleoprotein complex
GO:0005849 mRNA cleavage factor complex
GO:0006397 mRNA processing
GO:0042382 paraspeckles
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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