The protein encoded by CPSF6 gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. CPSF6 encodes the 68 kDa subunit. It has a domain organization reminiscent of spliceosomal proteins (provided by RefSeq, Jul 2008).
Rabbit anti Human CPSF6 antibody detects a band of 70 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
- Target Species
- Western Blotting
- Rabbit anti CPSF6 detects a band of approximately 70 kDa in Jurkat cell lysates
- Species Cross-Reactivity
Target Species Cross Reactivity Mouse
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Rabbit polyclonal antibody purified by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Synthetic peptide encompassing part of the middle region of human CPSF6
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
- GO:0000166 nucleotide binding
- GO:0005515 protein binding
- GO:0003723 RNA binding
- GO:0030529 ribonucleoprotein complex
- GO:0005849 mRNA cleavage factor complex
- GO:0006397 mRNA processing
- GO:0042382 paraspeckles
- PrecisionAb is a trademark of Bio-Rad Laboratories
- For research purposes only
Applications of CPSF6 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Secondary Antibodies Available
|Description||Product Code||Applications||Pack Size||List Price||Quantity|
|Goat anti Rabbit IgG (H/L):HRP||STAR208P||WB||2 ml|