Coro1A antibody

Rabbit anti Coro1A

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Coro1A

Product Code Applications Pack Size List Price Your Price Qty
AHP2457
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SDS Safety Datasheet SDS
WB 50 µl loader
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Rabbit anti CORO1A antibody recognizes coronin 1A (encoded by the CORO1A gene), also known as clipin-A, coronin-like protein p57 or tryptophan-aspartate-containing coat protein (TACO). Coronin 1A is a member of the WD repeat coronin protein family. Coronin 1A is expressed by leukocytes and is implicated in cytoskeleton remodeling.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse Expected from Sequence
Rat Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to CORO1A was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant human CORO1A
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti CORO1A antibody detects a band of approximately 56 kDa in Jurkat cell lysate under reducing conditions

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UniProt
P31146
Entrez Gene
CORO1A
GO Terms
GO:0001845 phagolysosome assembly
GO:0001891 phagocytic cup
GO:0051015 actin filament binding
GO:0008022 protein C-terminus binding
GO:0030027 lamellipodium
GO:0030670 phagocytic vesicle membrane
GO:0030864 cortical actin cytoskeleton
GO:0031589 cell-substrate adhesion
GO:0031941 filamentous actin
GO:0042803 protein homodimerization activity
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0045087 innate immune response
GO:0050918 positive chemotaxis
GO:0051126 negative regulation of actin nucleation
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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