COP9 Signalosome Complex Subunit 1 antibody

Rabbit anti COP9 Signalosome Complex Subunit 1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
COP9 Signalosome Complex Subunit 1

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VPA00254
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Rabbit anti Human COP9 signalosome complex subunit 1 antibody recognizes COP9 signalosome complex subunit 1, also known as GPS-1, JAB1-containing signalosome subunit 1, SGN1 and signalosome subunit 1.

GPS1, the gene encoding COP9 signalosome complex subunit 1, is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. COP9 signalosome complex subunit 1 shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding different isoforms have been found for GPS1 (provided by RefSeq, Jul 2008).

Rabbit anti Human COP9 signalosome complex subunit 1 antibody detects a band of 58 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti COP9 signalosome complex subunit 1 detects a band of approximately 58 kDa in HEK293 cell lysates.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
KLH conjugated synthetic peptide between 141-170 amino acids from the central region of human COP9 signalosome complex subunit 1
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
Q13098
Entrez Gene
GPS1
GO Terms
GO:0000188 inactivation of MAPK activity
GO:0005515 protein binding
GO:0005095 GTPase inhibitor activity
GO:0005737 cytoplasm
GO:0007049 cell cycle
GO:0007254 JNK cascade
GO:0008180 signalosome
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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