Complement Factor H antibody
Goat anti Human complement factor H antibody recognizes complement factor H, also known as H factor 1.
CFH, the gene encoding complement factor H, is a member of the regulator of complement activation (RCA) gene cluster. Complement factor H contains twenty short consensus repeat (SCR) domains, is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in complement factor H have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized (provided by RefSeq, Oct 2011).
Goat anti Human complement factor H antibody detects a band of 155 kDa. The antibody has been extensively validated for western blotting using human plasma samples.
CFH, the gene encoding complement factor H, is a member of the regulator of complement activation (RCA) gene cluster. Complement factor H contains twenty short consensus repeat (SCR) domains, is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in complement factor H have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized (provided by RefSeq, Oct 2011).
Goat anti Human complement factor H antibody detects a band of 155 kDa. The antibody has been extensively validated for western blotting using human plasma samples.
Product Details
- Target Species
- Human
- Western Blotting
- Anti complement factor H detects a band of approximately 155 kDa in human plasma samples.
- Product Form
- Purified IgG - liquid
- Preparation
- Goat polyclonal antibody purified by affinity chromatography
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3) 0.5% BSA
- Immunogen
- Peptide with the sequence C-HLVPDRKKDQYK, from the internal region of the protein sequence
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P08603
- Entrez Gene
- CFH
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of Complement Factor H antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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