Complement Factor H antibody

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Goat anti Complement Factor H

Complement factor H antibody recognizes complement factor H, also known as H factor 1 (complement), H factor 2 (complement), adrenomedullin binding protein, or age-related maculopathy susceptibility.

Product Type
PrecisionAb™ Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
VPA00158 WB 100 µl
Goat anti Human complement factor H antibody recognizes complement factor H, also known as H factor 1.

CFH, the gene encoding complement factor H, is a member of the regulator of complement activation (RCA) gene cluster. Complement factor H contains twenty short consensus repeat (SCR) domains, is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in complement factor H have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized (provided by RefSeq, Oct 2011).

Goat anti Human complement factor H antibody detects a band of 155 kDa. The antibody has been extensively validated for western blotting using human plasma samples.

Product Details

Target Species
Human
Western Blotting
Anti complement factor H detects a band of approximately 155 kDa in human plasma samples.
Product Form
Purified IgG - liquid
Preparation
Goat polyclonal antibody purified by affinity chromatography
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
0.02% Sodium Azide (NaN3) 0.5% BSA
Immunogen
Peptide with the sequence C-HLVPDRKKDQYK, from the internal region of the protein sequence
Instructions For Use
Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Shelf Life
As supplied, 12 months from date of despatch.

More Information

UniProt
P08603 Related reagents
Entrez Gene
CFH Related reagents
Acknowledgements
PrecisionAb™ is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of Complement Factor H antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Donkey anti Sheep/Goat IgG:HRP STAR88P 1 ml C E P WB

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