Complement Factor H antibody

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Goat anti Complement Factor H

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00158
Datasheet
WB
SDS
100 µl

Goat anti Human complement factor H antibody recognizes complement factor H, also known as H factor 1.

CFH, the gene encoding complement factor H, is a member of the regulator of complement activation (RCA) gene cluster. Complement factor H contains twenty short consensus repeat (SCR) domains, is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in complement factor H have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized (provided by RefSeq, Oct 2011).

Goat anti Human complement factor H antibody detects a band of 155 kDa. The antibody has been extensively validated for western blotting using human plasma samples.

Product Details

Target Species
Human
Western Blotting
Anti complement factor H detects a band of approximately 155 kDa in human plasma samples.
Product Form
Purified IgG - liquid
Preparation
Goat polyclonal antibody purified by affinity chromatography
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
0.02% Sodium Azide (NaN3) 0.5% BSA
Immunogen
Peptide with the sequence C-HLVPDRKKDQYK, from the internal region of the protein sequence

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
12 months from date of despatch

More Information

UniProt
P08603
Entrez Gene
CFH
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of Complement Factor H antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Donkey anti Sheep/Goat IgG:HRP STAR88P C E P WB 1 ml loader