CELF1 antibody

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Anti CELF1 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with CELF1 antibody followed by detection with HRP conjugated Goat anti Rabbit (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 160 second exposure. Arrow points to CELF1 (molecular weight 52 kDa)

Rabbit anti CELF1

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: CELF1

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VPA00386 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human CELF1 antibody recognizes the CUGBP Elav-like family member 1, also known as CUG binding protein 1, 50 kDa nuclear polyadenylated RNA-binding protein, bruno-like protein 2, embryo deadenylation element binding protein and nuclear polyadenylated RNA-binding protein, 50 kDa.

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. CELF1 may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms (provided by RefSeq, Jul 2008).

Rabbit anti Human CELF1 antibody detects a band of 52 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti CELF1 detects a band of approximately 52 kDa in HeLa cell lysate
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃).
Immunogen: KLH-conjugated synthetic peptide corresponding to aa 1-30 of human CELF1
Regulatory: For research purposes only
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Mouse

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: Q92879
Entrez Gene: CELF1
GO Terms: GO:0000166 nucleotide binding; GO:0005515 protein binding; GO:0000900 translation repressor activity, nucleic acid binding; GO:0003729 mRNA binding; GO:0030529 ribonucleoprotein complex; GO:0005634 nucleus; GO:0005737 cytoplasm; GO:0006376 mRNA splice site selection; GO:0007281 germ cell development; View More GO Terms; GO:0009790 embryo development; GO:0016246 RNA interference; GO:0042835 BRE binding; GO:0043484 regulation of RNA splicing