CDK6 (pTyr13) antibody
Rabbit anti Cdk6 (pTyr13) recognizes cyclin-dependent kinase 6 (CDK6) also known as cell division protein kinase 6 or serine/threonine-protein kinase PLSTIRE, when phosphorylated at tyrosine 13. CDK6 is a member of the serine/threonine protein kinase family and is involved in regulation of cell-cycle progression during G1 phase and transition from G1 to S phase.
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to Cdk6 (pTyr13) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
50% Glycerol - Immunogen
- Phospho specific-peptide corresponding to residues surrounding tyrosine 13 of human Cdk6
Storage Information
- Storage
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q00534
- Entrez Gene
- CDK6
- GO Terms
- GO:0000080 G1 phase of mitotic cell cycle
- GO:0000307 cyclin-dependent protein kinase holoenzyme complex
- GO:0001726 ruffle
- GO:0001954 positive regulation of cell-matrix adhesion
- GO:0009615 response to virus
- GO:0005829 cytosol
- GO:0004693 cyclin-dependent protein kinase activity
- GO:0005524 ATP binding
- GO:0005634 nucleus
- GO:0006468 protein phosphorylation
- GO:0010468 regulation of gene expression
- GO:0030332 cyclin binding
- GO:0042063 gliogenesis
- GO:0043697 cell dedifferentiation
- GO:0045646 regulation of erythrocyte differentiation
- GO:0045668 negative regulation of osteoblast differentiation
- GO:0045786 negative regulation of cell cycle
- GO:0048146 positive regulation of fibroblast proliferation
- GO:0050680 negative regulation of epithelial cell proliferation
- GO:0051301 cell division
- Regulatory
- For research purposes only
Applications of CDK6 (pTyr13) antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/500 | 1/2000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Useful Reagents Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml |
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