Rabbit anti CDC42 antibody recognizes cell division control protein 42 homolog (CDC42) also known as G25K GTP-binding protein. CDC42 is a small GTPase that plays a role in mediating cell migration, fillopodia formation and cell polarization. Based on sequence homology, this antibody may react with Rac protein family members.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 30% Glycerol
0.5% Bovine Serum Albumin
- Synthetic peptides surrounding amino acid 144 of human CDC42
- Approx. Protein Concentrations
- IgG concentration 0.2 mg/ml
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
actin cytoskeleton organization
establishment or maintenance of cell polarity
epidermal growth factor receptor signaling pathway
small GTPase mediated signal transduction
positive regulation of pseudopodium assembly
T cell costimulation
negative regulation of protein complex assembly
negative regulation of epidermal growth factor receptor signaling pathway
muscle cell differentiation
regulation of small GTPase mediated signal transduction
positive regulation of muscle cell differentiation
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of CDC42 antibody
|Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti CDC42 antibody recognizes a band of approximately 21 kDa in 3T3 and Jurkat cell lysates
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Secondary Antibodies Available