CD61 antibody

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Anti CD61 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with CD61 antibody followed by detection with HRP conjugated Goat anti Rabbit IgG (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 6 second exposure. Arrow points to CD61 (molecular weight 97-130 kDa)

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Rabbit anti CD61

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: CD61

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VPA00632 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human CD61 antibody recognizes integrin beta-3, also known as integrin beta-3, GPIIIa, platelet membrane glycoprotein IIIa.

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling (provided by RefSeq, Jul 2008).

Rabbit anti Human CD61 antibody detects a band of 97-130 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Rabbit anti CD61 detects a band of approximately 97-130 kDa in HEK293 cell lysates.
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide.
Immunogen: KLH conjugated synthetic peptide of partial human CD61 (amino acids 734 - 760)
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Mouse

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: P05106
Entrez Gene: ITGB3
GO Terms: GO:0001938 positive regulation of endothelial cell proliferation; GO:0002576 platelet degranulation; GO:0050839 cell adhesion molecule binding; GO:0004872 receptor activity; GO:0005161 platelet-derived growth factor receptor binding; GO:0008305 integrin complex; GO:0007160 cell-matrix adhesion; GO:0007229 integrin-mediated signaling pathway; GO:0007411 axon guidance; View More GO Terms; GO:0042802 identical protein binding; GO:0010595 positive regulation of endothelial cell migration; GO:0010745 negative regulation of macrophage derived foam cell differentiation; GO:0010888 negative regulation of lipid storage; GO:0014909 smooth muscle cell migration; GO:0030168 platelet activation; GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway; GO:0031092 platelet alpha granule membrane; GO:0032147 activation of protein kinase activity; GO:0032369 negative regulation of lipid transport; GO:0035295 tube development; GO:0043184 vascular endothelial growth factor receptor 2 binding; GO:0044419 interspecies interaction between organisms; GO:0045124 regulation of bone resorption; GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0050748 negative regulation of lipoprotein metabolic process; GO:0050900 leukocyte migration; GO:0060055 angiogenesis involved in wound healing; GO:0071062 alphav-beta3 integrin-vitronectin complex