CD282 antibody



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WB P ResetRabbit anti Human CD282 (N-Terminal)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- CD282
- Region
- (N-TERMINAL)
Rabbit anti Human CD282 antibody recognises CD282, also known as TLR-2, a ~90 kDa type 1 transmembrane protein that is primarily expressed by peripheral blood monocytes. CD282 is also expressed in the spleen, bone marrow and lymph nodes. CD282 is reported to respond to a diverse range of bacterial cell wall components, mediating the innate immune response in co-operation with MD-2. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Horse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to Human CD282 (NT) were raised by repeated immunisation of Rabbits with highly purified antigen. Purified IgG prepared from whole serum by ion exchange chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3)
- Immunogen
- A peptide corresponding to an 14 amino acid sequence from near the amino terminus of human CD282.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Paraffin 1 | ![]() |
2.0ug | |
Western Blotting | ![]() |
1.0ug/ml |
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.
- Histology Positive Control Tissue
- Human spleen
- Western Blotting
- AHP1635 detects a band of approximately 100kDa in A-20 cell lysate
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Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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Description | Sheep anti Rabbit IgG:FITC | ||||||
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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Description | Sheep anti Rabbit IgG:RPE |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
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Antigen Retrieval Buffer, pH8.0 | BUF025A | P | 500 ml | Log in | |||
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Description | Antigen Retrieval Buffer, pH8.0 | ||||||
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml | Log in | |||
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Description | TidyBlot Western Blot Detection Reagent:HRP |
References for CD282 antibody
-
Siemieniuch MJ et al. (2016) Type of Inflammation Differentially Affects Expression of Interleukin 1β and 6, Tumor Necrosis Factor-α and Toll-Like Receptors in Subclinical Endometritis in Mares.
PLoS One. 11 (5): e0154934.
Further Reading
-
Vogel, S.N. et al. (2003) TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression.
Mol Interv. 3 (8): 466-77. -
Takeda, K. et al. (2003) Toll-like receptors.
Annu Rev Immunol. 21: 335-76. -
Janeway, C.A. Jr. & Medzhitov, R. (2002) Innate immune recognition.
Annu Rev Immunol. 20: 197-216. -
O'Neill, L.A.J, et al (2003) The Toll-IL-1 receptor adaptor family grows to five members.
Trends in Imm. 24:286-9.
- Synonyms
- TLR2
- RRID
- AB_2204578
- UniProt
- O60603
- Entrez Gene
- TLR2
- GO Terms
- GO:0001875 lipopolysaccharide receptor activity
- GO:0002755 MyD88-dependent toll-like receptor signaling pathway
- GO:0004888 transmembrane receptor activity
- GO:0005887 integral to plasma membrane
- GO:0005737 cytoplasm
- GO:0006917 induction of apoptosis
- GO:0006954 inflammatory response
- GO:0007252 I-kappaB phosphorylation
- GO:0008063 Toll signaling pathway
- View More GO Terms
- GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
- GO:0030177 positive regulation of Wnt receptor signaling pathway
- GO:0032722 positive regulation of chemokine production
- GO:0032728 positive regulation of interferon-beta production
- GO:0032735 positive regulation of interleukin-12 production
- GO:0032741 positive regulation of interleukin-18 production
- GO:0032755 positive regulation of interleukin-6 production
- GO:0032757 positive regulation of interleukin-8 production
- GO:0032760 positive regulation of tumor necrosis factor production
- GO:0034123 positive regulation of toll-like receptor signaling pathway
- GO:0034130 toll-like receptor 1 signaling pathway
- GO:0034134 toll-like receptor 2 signaling pathway
- GO:0034142 toll-like receptor 4 signaling pathway
- GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex
- GO:0042346 positive regulation of NF-kappaB import into nucleus
- GO:0042495 detection of triacyl bacterial lipopeptide
- GO:0042496 detection of diacyl bacterial lipopeptide
- GO:0042497 triacyl lipopeptide binding
- GO:0042834 peptidoglycan binding
- GO:0045087 innate immune response
- GO:0046982 protein heterodimerization activity
- GO:0050729 positive regulation of inflammatory response
- GO:0051092 positive regulation of NF-kappaB transcription factor activity
- GO:0051637 Gram-positive bacterial cell surface binding
- GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process
- GO:0071223 cellular response to lipoteichoic acid
- GO:0071726 cellular response to diacyl bacterial lipopeptide
- GO:0071727 cellular response to triacyl bacterial lipopeptide
AHP1635



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