CD271 antibody

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Rabbit anti CD271

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00240
Datasheet
WB
SDS
100 µl loader

Rabbit anti Human CD271 antibody recognizes the CD271 antigen, also known as tumor necrosis factor (TNF) receptor superfamily member 16, NGF receptor, low affinity nerve growth factor receptor, low affinity neurotrophin receptor p75NTR and low-affinity nerve growth factor receptor, p75 ICD.

CD271 contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain (provided by RefSeq, Jul 2008).

Rabbit anti Human CD271 antibody detects a band of 75 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti CD271 detects a band of approximately 75 kDa in Raji cell lysates
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
KLH conjugated synthetic peptide between 276-310 amino acids from the C-terminal region of human CD271

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
12 months from date of despatch

More Information

UniProt
P08138
Entrez Gene
NGFR
GO Terms
GO:0006915 apoptosis
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0005887 integral to plasma membrane
GO:0005654 nucleoplasm
GO:0005768 endosome
GO:0006916 anti-apoptosis
GO:0008624 induction of apoptosis by extracellular signals
GO:0009986 cell surface
GO:0031293 membrane protein intracellular domain proteolysis
GO:0045786 negative regulation of cell cycle
GO:0048011 nerve growth factor receptor signaling pathway
GO:0050771 negative regulation of axonogenesis
GO:0050772 positive regulation of axonogenesis
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of CD271 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml