CD226 antibody

Rabbit anti CD226

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
CD226

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VPA00420
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Rabbit anti Human CD226 antibody recognizes CD226, also known as DNAX accessory molecule 1, T lineage-specific activation antigen 1 antigen, PTA1 and T cell activation antigen 1.

The CD226 antigen is a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation (provided by RefSeq, Jul 2008).

Rabbit anti Human CD226 antibody detects a band of 34 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti CD226 detects a band of approximately 34 kDa in Raji cell lysate.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
KLH-conjugated synthetic peptide corresponding to aa 307-335 of human CD226
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
Q15762
Entrez Gene
CD226
GO Terms
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0002891 positive regulation of immunoglobulin mediated immune response
GO:0007155 cell adhesion
GO:0050839 cell adhesion molecule binding
GO:0004872 receptor activity
GO:0005887 integral to plasma membrane
GO:0005178 integrin binding
GO:0008037 cell recognition
GO:0009986 cell surface
GO:0019901 protein kinase binding
GO:0033005 positive regulation of mast cell activation
GO:0045121 membrane raft
GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway
View more products with CD226 specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products