CD184 / CXCR4 antibody

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P ResetGoat anti Human CD184 / CXCR4
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- CD184 / CXCR4
- Region
- (N-TERMINAL)
Goat anti Human CD184 / CXCR4 antibody recognizes an epitope within the N-terminal (NT) region of human CD184, otherwise known as CXCR4 (C-X-C chemokine receptor type 4), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, ubiquitously expressed in blood and tissue cells, which acts as a specific receptor for the chemokine SDF-1 (Stromal cell-derived factor 1). Interaction of CD184 with SDF-1 mediates the chemotaxis of progenitor and mature blood cells, and is critical for B- lymphopoiesis and myelopoiesis. CD184 is a major co-receptor for infection by T-cell tropic strains of HIV1, and also a primary receptor for some HIV2 isolates. Goat anti Human CD184 / CXCR4 antibody is being suitable for use in immunofluorescence. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to human CD184 / CXCR4 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
0.1% Bovine Serum Albumin - Immunogen
- Synthetic peptide TEEMGSGDYDSMKEPCFREENANFNKC corresponding to amino acids 17-43 within the N-terminal region of human CD184 / CXCR4.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | ![]() |
1/25000 | |
Immunohistology - Paraffin | ![]() |
1/150 | |
Western Blotting | ![]() |
1/250 |
- Histology Positive Control Tissue
- Spleen
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Rabbit anti Goat IgG (Fc):FITC | STAR122F | F | 1 mg |
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Description | Rabbit anti Goat IgG (Fc):FITC | ||||||
Rabbit anti Goat IgG (Fc):HRP | STAR122P | C E WB | 1 mg |
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Description | Rabbit anti Goat IgG (Fc):HRP |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Antigen Retrieval Buffer, pH8.0 | BUF025A | P | 500 ml | Log in | |||
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Description | Antigen Retrieval Buffer, pH8.0 |
- RRID
- AB_2089655
- UniProt
- P61073
- O08565
- Entrez Gene
- Cxcr4
- CXCR4
- GO Terms
- GO:0005886 plasma membrane
- GO:0001764 neuron migration
- GO:0002064 epithelial cell development
- GO:0016021 integral to membrane
- GO:0005768 endosome
- GO:0008038 neuron recognition
- GO:0016493 C-C chemokine receptor activity
- GO:0016494 C-X-C chemokine receptor activity
- GO:0022029 telencephalon cell migration
- View More GO Terms
- GO:0043067 regulation of programmed cell death
- GO:0050920 regulation of chemotaxis
- GO:0051924 regulation of calcium ion transport
- GO:0060048 cardiac muscle contraction
- GO:0000187 activation of MAPK activity
- GO:0001666 response to hypoxia
- GO:0003779 actin binding
- GO:0009615 response to virus
- GO:0006915 apoptosis
- GO:0006954 inflammatory response
- GO:0007204 elevation of cytosolic calcium ion concentration
- GO:0009986 cell surface
- GO:0015026 coreceptor activity
- GO:0016023 cytoplasmic membrane-bounded vesicle
- GO:0019059 initiation of viral infection
- GO:0030260 entry into host cell
- GO:0031252 cell leading edge
- GO:0031625 ubiquitin protein ligase binding
- GO:0032027 myosin light chain binding
- GO:0043130 ubiquitin binding
AHP1808

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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