CD156b antibody
Rabbit anti Human CD156b antibody recognises the C-terminal region of the TNF alpha converting enzyme (TACE), designated CD156b at the 6th leukocyte typing workshop. TACE is a membrane-bound metalloprotease disintegrin belonging to the mammalian ADAM family.
Product Details
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to CD156b were raised by repeated immunisation of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.02% Sodium Azide - Immunogen
- Peptide corresponding to amino acids 807 to 823 of human CD156b
- Approx. Protein Concentrations
- IgG concentration 1 mg/ml
Storage Information
- Storage
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P78536
- Entrez Gene
- ADAM17
- GO Terms
- GO:0001666 response to hypoxia
- GO:0001934 positive regulation of protein phosphorylation
- GO:0002446 neutrophil mediated immunity
- GO:0002467 germinal center formation
- GO:0004222 metalloendopeptidase activity
- GO:0005887 integral to plasma membrane
- GO:0005138 interleukin-6 receptor binding
- GO:0005178 integrin binding
- GO:0005737 cytoplasm
- GO:0007173 epidermal growth factor receptor signaling pathway
- GO:0007219 Notch signaling pathway
- GO:0008270 zinc ion binding
- GO:0008284 positive regulation of cell proliferation
- GO:0042493 response to drug
- GO:0009986 cell surface
- GO:0010820 positive regulation of T cell chemotaxis
- GO:0015629 actin cytoskeleton
- GO:0016324 apical plasma membrane
- GO:0017124 SH3 domain binding
- GO:0030165 PDZ domain binding
- GO:0030183 B cell differentiation
- GO:0030307 positive regulation of cell growth
- GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
- GO:0031293 membrane protein intracellular domain proteolysis
- GO:0031659 positive regulation of cyclin-dependent protein kinase activity involved in G1/S
- GO:0032496 response to lipopolysaccharide
- GO:0032717 negative regulation of interleukin-8 production
- GO:0032722 positive regulation of chemokine production
- GO:0033025 regulation of mast cell apoptosis
- GO:0033077 T cell differentiation in thymus
- GO:0033627 cell adhesion mediated by integrin
- GO:0035313 wound healing, spreading of epidermal cells
- GO:0035625 epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway
- GO:0045121 membrane raft
- GO:0048011 nerve growth factor receptor signaling pathway
- GO:0048536 spleen development
- GO:0051088 PMA-inducible membrane protein ectodomain proteolysis
- GO:0055099 response to high density lipoprotein particle stimulus
- Regulatory
- For research purposes only
Applications of CD156b antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/500 |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
|
|
| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
|
|
| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
|
|
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
|
|
| Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
|
|
| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
|
|
| Sheep anti Rabbit IgG:DyLight®488 | STAR36D488GA | F IF WB | 0.1 mg | ||
| Sheep anti Rabbit IgG:DyLight®680 | STAR36D680GA | F IF WB | 0.1 mg | ||
| Sheep anti Rabbit IgG:Dylight®800 | STAR36D800GA | F IF WB | 0.1 mg |
Useful Reagents Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml |
Product Specific References
Further Reading
-
Moss, M.L. et al. (1997) Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha.
Nature. 385 (6618): 733-6.
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