Rabbit anti Human CD156b antibody recognises the C-terminal region of the TNF alpha converting enzyme (TACE), designated CD156b at the 6th leukocyte typing workshop. TACE is a membrane-bound metalloprotease disintegrin belonging to the mammalian ADAM family.
- Target Species
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to CD156b were raised by repeated immunisation of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Peptide corresponding to amino acids 807 to 823 of human CD156b
- Approx. Protein Concentrations
- IgG concentration 1 mg/ml
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
response to hypoxia
positive regulation of protein phosphorylation
neutrophil mediated immunity
germinal center formation
integral to plasma membrane
interleukin-6 receptor binding
epidermal growth factor receptor signaling pathway
Notch signaling pathway
zinc ion binding
positive regulation of cell proliferation
response to drug
positive regulation of T cell chemotaxis
apical plasma membrane
SH3 domain binding
PDZ domain binding
B cell differentiation
positive regulation of cell growth
positive regulation of transforming growth factor beta receptor signaling pathway
membrane protein intracellular domain proteolysis
positive regulation of cyclin-dependent protein kinase activity involved in G1/S
response to lipopolysaccharide
negative regulation of interleukin-8 production
positive regulation of chemokine production
regulation of mast cell apoptosis
T cell differentiation in thymus
cell adhesion mediated by integrin
wound healing, spreading of epidermal cells
epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway
nerve growth factor receptor signaling pathway
PMA-inducible membrane protein ectodomain proteolysis
response to high density lipoprotein particle stimulus
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of CD156b antibody
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
Useful Reagents Available
Product Specific References
Moss, M.L. et al. (1997) Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha.
Nature. 385 (6618): 733-6.
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