CD156b antibody

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Anti Human CD156b (C-Terminal) Antibody thumbnail image 1

Anti Human CD156b (C-Terminal) Antibody thumbnail image 2

Anti Human CD156b (C-Terminal) Antibody gallery image 1 — Western blot analysis of CD156b (TACE) in HeLa (1,3) and Jurkat (2,4) whole cell lysate in the absence (1,2) or presence (3,4) of blocking peptide probed with Rabbit anti Human CD156b (AHP589)

Anti Human CD156b (C-Terminal) Antibody gallery image 2 — Immunocytochemical staining of HeLa cells with Rabbit anti Human CD156b (AHP589)

Rabbit anti Human CD156b (C-Terminal)

Product Type: Polyclonal Antibody
Isotype: Polyclonal IgG

Product Code	Applications	Datasheet	MSDS	Pack Size	List Price	Quantity
AHP589	WB			0.1 mg

Rabbit anti Human CD156b antibody recognises the C-terminal region of the TNF alpha converting enzyme (TACE), designated CD156b at the 6th leukocyte typing workshop. TACE is a membrane-bound metalloprotease disintegrin belonging to the mammalian ADAM family.

Product Details

Target Species

Human

Product Form

Purified IgG - liquid

Antiserum Preparation

Antisera to CD156b were raised by repeated immunisation of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

0.02%

Sodium Azide

Immunogen

Peptide corresponding to amino acids 807 to 823 of human CD156b

Approx. Protein Concentrations

IgG concentration 0.5 mg/ml

Storage Information

Storage: Store at +4^oC or at -20^oC if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

More Information

UniProt: P78536 Related reagents
Entrez Gene: ADAM17 Related reagents
GO Terms: GO:0001666 response to hypoxia; GO:0001934 positive regulation of protein phosphorylation; GO:0002446 neutrophil mediated immunity; GO:0002467 germinal center formation; GO:0004222 metalloendopeptidase activity; GO:0005887 integral to plasma membrane; GO:0005138 interleukin-6 receptor binding; GO:0005178 integrin binding; GO:0005737 cytoplasm; GO:0007173 epidermal growth factor receptor signaling pathway; GO:0007219 Notch signaling pathway; GO:0008270 zinc ion binding; GO:0008284 positive regulation of cell proliferation; GO:0042493 response to drug; GO:0009986 cell surface; GO:0010820 positive regulation of T cell chemotaxis; GO:0015629 actin cytoskeleton; GO:0016324 apical plasma membrane; GO:0017124 SH3 domain binding; GO:0030165 PDZ domain binding; GO:0030183 B cell differentiation; GO:0030307 positive regulation of cell growth; GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway; GO:0031293 membrane protein intracellular domain proteolysis; GO:0031659 positive regulation of cyclin-dependent protein kinase activity involved in G1/S; GO:0032496 response to lipopolysaccharide; GO:0032717 negative regulation of interleukin-8 production; GO:0032722 positive regulation of chemokine production; GO:0033025 regulation of mast cell apoptosis; GO:0033077 T cell differentiation in thymus; GO:0033627 cell adhesion mediated by integrin; GO:0035313 wound healing, spreading of epidermal cells; GO:0035625 epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway; GO:0045121 membrane raft; GO:0048011 nerve growth factor receptor signaling pathway; GO:0048536 spleen development; GO:0051088 PMA-inducible membrane protein ectodomain proteolysis; GO:0055099 response to high density lipoprotein particle stimulus
Regulatory: For research purposes only

Applications of CD156b antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/500

Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description	Product Code	Pack Size	Applications
Sheep anti Rabbit IgG:Biotin	2AB02B	1 ml	C E P WB
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	1 mg	E WB
Goat anti Rabbit IgG (Fc):FITC	STAR121F	1 mg	F
Goat anti Rabbit IgG (Fc):HRP	STAR121P	1 mg	E WB
Goat anti Rabbit IgG (H/L):HRP	STAR124P	1 mg	C E WB
Sheep anti Rabbit IgG:FITC	STAR34B	1 mg	C F
Sheep anti Rabbit IgG:RPE	STAR35A	1 ml	F
Sheep anti Rabbit IgG:DyLight®488	STAR36D488GA	0.1 mg	F IF WB
Sheep anti Rabbit IgG:DyLight®549	STAR36D549GA	0.1 mg	F IF
Sheep anti Rabbit IgG:DyLight®649	STAR36D649GA	0.1 mg	F IF
Sheep anti Rabbit IgG:DyLight®680	STAR36D680GA	0.1 mg	F IF WB
Sheep anti Rabbit IgG:Dylight®800	STAR36D800GA	0.1 mg	F IF WB

Useful Reagents Available

Description	Product Code	Pack Size	Applications	List Price	Quantity
TidyBlot™ Western Blot Detection Reagent:HRP	STAR209P	0.5 ml	WB*